Protein Alignment Spn47C and SERPINA7

DIOPT Version :10

• Sequence 1: NP_610633.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: XP_006724746.1
• Gene: SERPINA7 / 6906
• HGNCID: 11583
• Length: 425
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 106/395 - (26%)
• Similarity: 180/395 - (45%)
• Gaps: 51/395 - (12%)

  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEVAKQHAES 82
            ||.||:|....|.|..|:..||....:|:.::..||...:..|:...|...:::...|..||.
Human    49 FAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHG-- 111

  Fly    83 WTDECSCA----KKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNPEDSVKKVNK 143
             .....|:    ||.:.|::...|::.:..|....|.:.....:..|.:|.::.|...:.:::|.
Human   112 -FQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINS 175

  Fly   144 WLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKW-NKIFPQQLTQIDDFWINPRQRMEVSMM 207
            .:|..|...|..|.  :....::.::|||.:.|:|:| |...|.:......|.|:....::|.||
Human   176 HVEMQTKGKVVGLI--QDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMM 238

  Fly   208 RQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDMNEVA--AKSLMK 270
            .|:.|:.:....:|...:||:.:.::.|.:.:        ||    |.||::..|.|  :|:|.|
Human   239 HQMEQYYHLVDMELNCTVLQMDYSKNALALFV--------LP----KEGQMESVEAAMSSKTLKK 291

  Fly   271 --------EVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFE---MKTPQK------ 318
                    .||:.:|||.|..|.||...|.||||...: :..||.|.|.|   :|...:
Human   292 WNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAY-SENADFSGLTEDNGLKLSNRPAGFVL 355

  Fly   319 ISEARHKVFLNVTEFGCEVA--PEAEV--QPEVLKKNPDRKFFKADRPFVFAIRDR--KNVYFVG 377
            .::|.||..|::.|.|.|.|  ||.|:  |||....:|   ..:.||.|:..|.:|  :::.|:|
Human   356 PTQAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHP---IIQIDRSFMLLILERSTRSILFLG 417

  Fly   378 HFVKP 382
            ..|.|
Human   418 KVVNP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_610633.1	serpin42Dd-like_insects	13..382	CDD:381070	105/393 (27%)
SERPINA7	XP_006724746.1	serpinA7_TBG	37..425	CDD:381023	106/395 (27%)