Protein Alignment Spn47C and Serpina12

DIOPT Version :10

• Sequence 1: NP_610633.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 386
• Identity: 99/386 - (25%)
• Similarity: 189/386 - (48%)
• Gaps: 22/386 - (5%)

  Fly     4 GGTTAPSLSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKL-IL 67
            |...|..|:...:.|...|.:.|....|..|:.:||....:|.:::.:||...:.:|:|... ..
Mouse    41 GKKDARQLARHNMEFGFKLLQRLASNSPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFK 105

  Fly    68 GVSNKSEVAKQH--AESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLN 130
            .:||....|..|  ......|....|    :.|...|:::::.:.:..|.::|...::|:....|
Mouse   106 EMSNWDVHAAFHYLLHKLNQETEDTK----MNLGNALFMDQKLRPQQRFLNLAKNVYDADMVLTN 166

  Fly   131 YLNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFW 195
            :.:.|::.|.:|:::.:.|...::|:.  :..:..:.:||.|.::||.:|...|..:.|:.::|:
Mouse   167 FQDLENTQKDINRYISQKTHSRIKNMV--KSIDPGTVMILTNYIYFRGRWQYEFDPKQTKEEEFF 229

  Fly   196 INPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDM 260
            |...:.::|.||.|.|.:......:|...||::|: |.|:|...:||.  :|..:|.|:..|.|:
Mouse   230 IEKGKTVKVPMMFQRGLYDMAYDSQLSCTILEIPY-RGNITATFVLPD--NGKLKLLEQGLQADI 291

  Fly   261 NEVAAKSLMKE--VDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEAR 323
             ....|||:.:  |||.:||.||..|.::|..|.::||:.:|:. ..||:.:...:: .|:.||.
Mouse   292 -FAKWKSLLSKRVVDVWVPKLRISSTYNMKKVLSRLGISKIFEE-NGDLTRISSHRS-LKVGEAV 353

  Fly   324 HKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIRDR--KNVYFVGHFVKP 382
            ||..|.:.|.|.|.|..:..| .:..:.|  :..|.||||:..|.:.  .::.|:.....|
Mouse   354 HKAELKMDEKGMEGAAGSGAQ-TLPMETP--RHMKLDRPFLMMIYENFMPSMVFLARIYDP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_610633.1	serpin42Dd-like_insects	13..382	CDD:381070	95/375 (25%)
Serpina12	NP_080811.1	serpinA12_vaspin	40..411	CDD:381026	98/384 (26%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		5/20 (25%)