DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpini2

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_080736.2	Gene:	Serpini2 / 67931	MGIID:	1915181	Length:	405	Species:	Mus musculus

Alignment Length:	399	Identity:	100/399 - (25%)
Similarity:	194/399 - (48%)	Gaps:	39/399 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SGGTTAPSLSASPIVFARNLFRAL-----NDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADE-L 61
            ||..|:.:.......||.:|::|:     |      |::.||.|....:.:|.:||.||:..: |
Mouse    14 SGSQTSRATDQKIADFAVDLYKAISLSHKN------NIIFSPLGTTMLLGMVQLGAKGKAQQQIL 72

  Fly    62 RSKLILGVSNKSEVAKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEA 126
            ::..:.|.....|.:.  .:|.....|..|:.....|.:.||:.|...::..:.....|||.:..
Mouse    73 KTLRMRGTPAGEEFSV--LKSLFSAISKKKQEFTFNLASALYLQEGFIVKETYLHSNKEFFQSAT 135

  Fly   127 YSLNYLNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQI 191
            ..:::|:.:.|.:.::.|:|..|...::|:|:.|.|...:.::|||:::|:..|.:.|.::.|::
Mouse   136 KLVDFLDAKTSAQAISTWVESKTDGKIKNMFSEEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTEM 200

  Fly   192 DDFWINPRQRMEVSMMRQI--GQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEK 254
            .||.......::|.||:.:  .|:.|.....:..|:|:||::....:::|||||....:.|:|
Mouse   201 TDFTKKDGSTVKVPMMKALLRAQYGYFSQSSMTCQVLELPYKADEFSLVIILPTEDTSIEEVE-- 263

  Fly   255 LGQLDMNEVAAKSLMK--------EVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLF 311
                  |:|.|..:.:        ||:|::|:|:||..:|||..|..:.:..:|..| .|||.:.
Mouse   264 ------NQVTAPHVRRWFSELHEEEVEVSLPRFKIEQKLDLKEALYSLNVTEIFSGG-CDLSGIT 321

  Fly   312 EMKTPQKISEARHKVFLNVTEFGCEVAPEAEVQ-PEVLKKNPDRKFFKADRPFVFAIRD--RKNV 373
            : .:...:|....|||..:.|.|.|.|....:. |.::.....:  |.|:.||:|.::.  .:::
Mouse   322 D-SSEVYVSRVMQKVFFEINEDGSEAAASTGINIPAIMSLTQTQ--FLANHPFLFILKHIRTESI 383

  Fly   374 YFVGHFVKP 382
            .|:|....|
Mouse   384 LFMGKVTDP 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	96/379 (25%)
Serpini2	NP_080736.2	neuroserpin	23..405	CDD:239003	97/390 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020