DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpinb11

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_080143.1	Gene:	Serpinb11 / 66957	MGIID:	1914207	Length:	388	Species:	Mus musculus

Alignment Length:	388	Identity:	103/388 - (26%)
Similarity:	190/388 - (48%)	Gaps:	33/388 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEVAKQHAES 82
            |..::|:.|:......|:..||.....|::::.:|..||||:::..  :|...:.|.|.|...::
Mouse    11 FCLDVFKELSSNNVGENIFFSPLTTFYALSMLLLGTRGKSAEQMEK--VLHYDSFSGVLKAKTKN 73

  Fly    83 WTDECSCAKKGV----------------ALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNY 131
            .::   |::.||                :|.:..|:|..........:.....:.:.|:..::::
Mouse    74 SSE---CSQVGVMHPDFRALISHINQQNSLSVANRIYGTRSISFHKQYVRCCEKLYQAKLQTVDF 135

  Fly   132 -LNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFW 195
             |:.|::.|.:|.|::..|...:.|||.....:..|.::||::::|:.:|...|.::.|....|.
Mouse   136 ELSTEETRKSINAWVKNKTNGKITNLFAKGTIDPSSVMVLVSAIYFKGQWQNKFQKRETVKAPFH 200

  Fly   196 INPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDM 260
            :...:...|:||.|.|.|:....|:.:.|:|:||:..:.|.|:|:||.....:.::|:.|....:
Mouse   201 MGVGKSAVVNMMYQTGTFKLAIIKEPEMQVLELPYANNKLRMIILLPVGTASVSQIEKHLNVKML 265

  Fly   261 NEVAAKSLM--KEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQK---IS 320
            .|....|.|  :||||.||||.:....||...|:.:|:..:|:...||||.:    :|.|   :|
Mouse   266 REWTNPSNMVEREVDVHIPKFSLSVKYDLNTLLKSLGMRDIFNVANADLSGM----SPDKGLYLS 326

  Fly   321 EARHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIRDRK-NVYFVGHFVKP 382
            :..||.:::|.|.|.|.| .|..:...:|:.|....|.|:.||:|.|.|.. |:.|.|.|..|
Mouse   327 KVVHKSYVDVNEEGTEAA-AATGESISVKRLPVTVQFTANCPFLFFIWDESGNILFAGKFASP 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	101/383 (26%)
Serpinb11	NP_080143.1	SERPIN	4..388	CDD:294093	102/386 (26%)
Serpinb11	NP_080143.1	RCL. /evidence=ECO:0000250	338..362		7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920