DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn47C and Serpina5

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001231668.1	Gene:	Serpina5 / 65051	RGDID:	619817	Length:	442	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	101/383 - (26%)
Similarity:	185/383 - (48%)	Gaps:	12/383 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASGGTTAPSLSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLI 66
            :|.|....|.|..   ||..|:|||..|.|..|:..||.....::.::.:|:|.|:..::...|.
  Rat    70 SSVGAVGTSRSRD---FAFRLYRALASEAPGQNVFFSPMSVSMSLGMLSLGSGLKTKAQILEGLG 131

  Fly    67 LGV-SNKSEVAKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLN 130
            |.: ..:.::..:..:....:.|....|:.|.|.:.|:.:....||..|.......:.::.:|.|
  Rat   132 LSLQQGQEDMLHKGFQQLLQQFSQPSDGLQLSLGSALFTDPAVHIRDHFLSAMKTLYMSDMFSTN 196

  Fly   131 YLNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFW 195
            :.|||.:.|::|.::.|.|...:.:|.  :..:|...:::||.:||:|||...|....|...|:.
  Rat   197 FGNPESAKKQINDYVAKKTNGKIVDLI--KDLDSTHVMVVVNYIFFKAKWQTAFSSTNTHKMDYH 259

  Fly   196 INPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDG-LPELEEKLGQLD 259
            :.|::.::|.||.:...:.|...:.:...::.:|:: .|...:.|||:  :| :..:|:.|.:..
  Rat   260 VTPKKTIQVPMMNREDIYSYILDQNISCTVVGIPYQ-GNTFALFILPS--EGKMKRVEDGLDERT 321

  Fly   260 MNEVAAKSLMKEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEARH 324
            :.........:::|:.:|||.||.|..|:..|.|:||..:|.. .||||.|.: .|..|:||..|
  Rat   322 LRNWLKMFTKRQLDLYLPKFSIEGTYKLEKILPKLGIQDIFTT-HADLSGLTD-HTNIKLSEMVH 384

  Fly   325 KVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIRDRKNVYFVGHFVKP 382
            |..:.|.|.|...|....:...:....|.....:..|||:..|.|..|:||:|..::|
  Rat   385 KSMVEVDESGTTAAASTGILFTLRSARPSSLKVEFTRPFLVVIMDGTNLYFIGKVIQP 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	96/362 (27%)
Serpina5	NP_001231668.1	alpha-1-antitrypsin_like	81..439	CDD:239011	96/367 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010