DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and serpini1

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001122164.1	Gene:	serpini1 / 557627	ZFINID:	ZDB-GENE-060503-390	Length:	415	Species:	Danio rerio

Alignment Length:	393	Identity:	108/393 - (27%)
Similarity:	188/393 - (47%)	Gaps:	48/393 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSN-KSEVAKQHAE 81
            |:..|:..|.......|::.||.....|:.:|.:||.|.|..|:|.  .:|.|: :.:.......
Zfish    31 FSVRLYHQLQISSGEENIIFSPLSVALALGMVELGARGSSLQEIRQ--AVGYSHFREDEEFSLLR 93

  Fly    82 SWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNPEDSVKKVNKWLE 146
            :.:...|..::...:||...|::........||..:..::|.||..::::.......:::|.|:.
Zfish    94 NLSQALSTDEEQYVVRLANSLFLQSGVHFNEDFLQLMKKYFRAEVETVDFSQSTAVAERINSWVL 158

  Fly   147 KHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWINPRQRMEVSMMRQIG 211
            .||...::||.:.|.|:|.:.::|||:::||..|...|..:.|:...|..:....::..||.|.|
Zfish   159 NHTESKIQNLVSAEDFSSSTMIMLVNAVYFRGSWKNQFRPENTRTFSFTRDDGSEVQTLMMYQQG 223

  Fly   212 QFRYGESKKLKS------QILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDMNEVAAKSLMK 270
            .|.|||.....:      |:|::.:|..:::|||:||.....|..||..:....:.|.|.....:
Zfish   224 DFYYGEFSDGTTEAGGVYQVLEMLYEGEDMSMMIVLPRQEVPLASLEPIIKAPLLEEWANNVKRQ 288

  Fly   271 EVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLS----------DLFEMKTPQKISEARHK 325
            :|:|.:|:|::|..:||:..||::||.|:| :..||||          |||       |.:|..|
Zfish   289 KVEVYLPRFKVEQKIDLRESLQQLGIRSIF-SKDADLSAMTAQMTDGQDLF-------IGKAVQK 345

  Fly   326 VFLNVTEFGCEVAPEA---------EVQPEVLKKNPDRKFFKADRPFVFAIRDRK--NVYFVGHF 379
            .:|.|||.|.|.|..:         .:.|:|:          ||.||.|.||:||  ::.|:|..
Zfish   346 AYLEVTEEGAEGAAGSGMIALTRTLVLYPQVM----------ADHPFFFIIRNRKTGSILFMGRV 400

  Fly   380 VKP 382
            :.|
Zfish   401 MNP 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	107/388 (28%)
serpini1	NP_001122164.1	SERPIN	25..414	CDD:294093	108/393 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.020