Protein Alignment Spn47C and SERPINF2

DIOPT Version :10

• Sequence 1: NP_610633.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: XP_005256758.2
• Gene: SERPINF2 / 5345
• HGNCID: 9075
• Length: 507
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 95/402 - (23%)
• Similarity: 180/402 - (44%)
• Gaps: 46/402 - (11%)

  Fly     4 GGTTA-----------PS------LSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFM 51
            ||.||           |:      |:.:.:.|..:||..:.......|:::||.....|::.:.:
Human    74 GGQTALKSPPGVCSRDPTPEQTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLAL 138

  Fly    52 GAGGKSADELRSKLILGVSNKSEVAKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFND 116
            ||...:...|:..|..|    |.....|..|..  |.....| |.||..|:|:.:...|:.||.:
Human   139 GAQNHTLQRLQQVLHAG----SGPCLPHLLSRL--CQDLGPG-AFRLAARMYLQKGFPIKEDFLE 196

  Fly   117 MALEFFNAEAYSLNYLNPEDSVKKVNKWLEKHTFYTVRNLFT--PEVFNSDSSVILVNSLFFRAK 179
            .:.:.|.|:..||.. ..||.:..:|:|:::.|...::...:  ||    |:.::|:|::.|:..
Human   197 QSEQLFGAKPVSLTG-KQEDDLANINQWVKEATEGKIQEFLSGLPE----DTVLLLLNAIHFQGF 256

  Fly   180 WNKIFPQQLTQIDDFWINPRQRMEVSMMR-QIGQFRYGESKKLKSQILQLPFERSNLTMMIILPT 243
            |...|...|||.|.|.::.:..:.|.||: :....|:...::.:.|:...|| ::|::.::::||
Human   257 WRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPF-KNNMSFVVLVPT 320

  Fly   244 AIDGLPELEEKLGQLDMNEVAAKSLM-KEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADL 307
            ..:.  .:.:.|..|..:.:....:. :...|.:||..::..:||...|.::|:..:|.|  .||
Human   321 HFEW--NVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQA--PDL 381

  Fly   308 SDLFEMKTPQKISEARHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAI-RDRK 371
            ..:.|...  .:|..:|:..|.::|.|.|.|....:....:..:.    |..:|||:|.| .|..
Human   382 RGISEQSL--VVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSS----FSVNRPFLFFIFEDTT 440

  Fly   372 NV-YFVGHFVKP 382
            .: .|||....|
Human   441 GLPLFVGSVRNP 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_610633.1	serpin42Dd-like_insects	13..382	CDD:381070	88/374 (24%)
SERPINF2	XP_005256758.2	serpinF2_A2AP	91..454	CDD:381009	90/385 (23%)