Protein Alignment Spn47C and SERPINI1

DIOPT Version :9

• Sequence 1: NP_001163116.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001116224.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 109/403 - (27%)
• Similarity: 193/403 - (47%)
• Gaps: 41/403 - (10%)

  Fly     1 MASGGTTAPSLSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKL 65
            ||:|.|......|...|...|..||..::   .|::.||.....||.::.:||.|.:..|:|..:
Human    15 MATGATFPEEAIADLSVNMYNRLRATGED---ENILFSPLSIALAMGMMELGAQGSTQKEIRHSM 76

  Fly    66 -ILGVSNKSEVAKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSL 129
             ...:.|..|.:  ..:.:::..:..:....:::...|:|.....:..:|..|..::|||....:
Human    77 GYDSLKNGEEFS--FLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHV 139

  Fly   130 NYLNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDF 194
            ::.........:|||:|.:|...|::|.:|..|::.:.:.|:|:::|:..|...|..:.|:...|
Human   140 DFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSF 204

  Fly   195 WINPRQRMEVSMMRQIGQFRYGESKKLKS------QILQLPFERSNLTMMIILPTAIDGLPELEE 253
            ..:....:::.||.|.|:|.|||.....:      |:|::|:|...::||::|......|..| |
Human   205 TKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATL-E 268

  Fly   254 KLGQLDMNEVAAKSLMKE-VDVTIPKFRIECTVDLKVPLQKMGINSVF--DAGQADLSDLFEMKT 315
            .|.:..:.|..|.|:.|: |:|.:|:|.:|..:|||..|:.:||..:|  ||....|||..|:
Human   269 PLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKEI-- 331

  Fly   316 PQKISEARHKVFLNVTEFGCEVAP---------EAEVQPEVLKKNPDRKFFKADRPFVFAIRDRK 371
              .:|:|.||.||.|.|.|.|.|.         .|.:.|:|:          .|.||.|.||:|:
Human   332 --FLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVI----------VDHPFFFLIRNRR 384

  Fly   372 --NVYFVGHFVKP 382
              .:.|:|..:.|
Human   385 TGTILFMGRVMHP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	102/381 (27%)
SERPINI1	NP_001116224.1	neuroserpin	23..410	CDD:239003	105/395 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920