Protein Alignment Spn47C and SERPINB6

DIOPT Version :9

• Sequence 1: NP_001163116.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 105/385 - (27%)
• Similarity: 182/385 - (47%)
• Gaps: 39/385 - (10%)

  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEVAKQHAES 82
            ||.||.:.|..: ...|:..||.....|:.:|:|||.|.:|.::...|....|.......|..:|
Human    89 FALNLLKTLGKD-NSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQS 152

  Fly    83 WTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNP-EDSVKKVNKWLE 146
            ...|.:.......||:..||:..:.....:.|.|...:|:.||...|::::. |.|.|.:|.|:.
Human   153 LLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVA 217

  Fly   147 KHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWINPRQRMEVSMMRQIG 211
            :.|...:..|.:|...:..:.::|||:::||..|::.|.::.|:...|.::..:...|.||.:..
Human   218 EKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS 282

  Fly   212 QFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKL--------GQLDMNEVAAKSL 268
            .|:.....::.:|||.||:....|.|:|:||.....|..:|::|        .:|||.:
Human   283 TFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMD------ 341

  Fly   269 MKEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEARHKVFLNVTEF 333
            .:||:|::|:|::|.:.|::..|:.:|:...|:.|:||.|.:  .:|...:|:..||.|:.|.|.
Human   342 EEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGM--SQTDLSLSKVVHKSFVEVNEE 404

  Fly   334 GCEVAPE---------AEVQPEVLKKNPDRKFFKADRPFVFAIRDRK--NVYFVGHFVKP 382
            |.|.|..         |...|.          |.||.||:|.|:..|  .:.|.|.|..|
Human   405 GTEAAAATAAIMMMRCARFVPR----------FCADHPFLFFIQHSKTNGILFCGRFSSP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	103/380 (27%)
SERPINB6	XP_011512974.1	PAI-2	82..454	CDD:239013	104/383 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820