Protein Alignment Spn47C and SERPINA1

DIOPT Version :9

• Sequence 1: NP_001163116.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 110/385 - (28%)
• Similarity: 195/385 - (50%)
• Gaps: 32/385 - (8%)

  Fly     9 PSLSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKS 73
            |:|:.    ||.:|:|.|..:....|:..||....:|..::.:|....:.||:...|..   |.:
Human    52 PNLAE----FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNF---NLT 109

  Fly    74 EVAKQHAESWTDEC--SCAKKGVALRLVT--RLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNP 134
            |:.:........|.  :..:....|:|.|  .|:::|..|:...|.:...:.:::||:::|:.:.
Human   110 EIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

  Fly   135 EDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWINPR 199
            |::.|::|.::||.|...:.:|.  :..:.|:...|||.:||:.||.:.|..:.|:.:||.::..
Human   175 EEAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQV 237

  Fly   200 QRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDG-LPELEEKLGQLDMNEV 263
            ..::|.||:::|.|.....|||.|.:|.:.: ..|.|.:..||.  :| |..||.:|    .:::
Human   238 TTVKVPMMKRLGMFNIQHCKKLSSWVLLMKY-LGNATAIFFLPD--EGKLQHLENEL----THDI 295

  Fly   264 AAKSLMKE----VDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEARH 324
            ..|.|..|    ..:.:||..|..|.|||..|.::||..||..| ||||.:.| :.|.|:|:|.|
Human   296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTE-EAPLKLSKAVH 358

  Fly   325 KVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAI--RDRKNVYFVGHFVKP 382
            |..|.:.|.|.|.|....::...:...|:.||   ::||||.:  ::.|:..|:|..|.|
Human   359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF---NKPFVFLMIEQNTKSPLFMGKVVNP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	106/371 (29%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	106/377 (28%)
		RCL	368..392		6/26 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010