Protein Alignment Spn47C and SERPINA5

DIOPT Version :9

• Sequence 1: NP_001163116.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 104/390 - (26%)
• Similarity: 184/390 - (47%)
• Gaps: 31/390 - (7%)

  Fly     4 GGTTAPSLSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILG 68
            |.|.|||   |...|..:|:|||....|..::..||.....::.::.:|||..:..::...|.|.
Human    37 GATVAPS---SRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLN 98

  Fly    69 VSNKSEVAKQHA-ESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYL 132
            :...||...... :....|.:..:.|..|.|...|:.:....::..|.......:.|:.:..|:.
Human    99 LQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFR 163

  Fly   133 NPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWIN 197
            :...::|::|.::.|.|...:.:|.  :..:|::.||:||.:||:|||...|..:.||..||::.
Human   164 DSAGAMKQINDYVAKQTKGKIVDLL--KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 226

  Fly   198 PRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDMNE 262
            ....:.|.||.:..|:.|...:.|..:::.:|:: .|.|.:.|||:        |.|:.|:: |.
Human   227 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQ-GNATALFILPS--------EGKMQQVE-NG 281

  Fly   263 VAAKSLMK--------EVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKI 319
            ::.|:|.|        ::::.:|||.||.:..|:..|..:||::|| ...||||.:......| :
Human   282 LSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVF-TSHADLSGISNHSNIQ-V 344

  Fly   320 SEARHKVFLNVTEFGCEVAPEAEV--QPEVLKKNPDRKFFKADRPFVFAIRDRKNVYFVGHFVKP 382
            ||..||..:.|.|.|...|.....  .....:.|..|..|  :|||:..|.| .|:.|:|...:|
Human   345 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVF--NRPFLMFIVD-NNILFLGKVNRP 406

  Fly   383  382
            Human   407  406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	97/371 (26%)
SERPINA5	NP_000615.3	alpha-1-antitrypsin_like	44..403	CDD:239011	98/375 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6025
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.960