Protein Alignment Spn47C and SERPINB2

DIOPT Version :9

• Sequence 1: NP_001163116.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001137290.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 113/439 - (25%)
• Similarity: 195/439 - (44%)
• Gaps: 94/439 - (21%)

  Fly    11 LSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEV 75
            |..:..:||.|||:.|....|..|:.:||....|.|.:|:||:.|.:.|::...|.......:.|
Human     4 LCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAV 68

  Fly    76 AKQHAESWTDECSCA-----KKG--------------------------------VALRLVTRLY 103
            .....|::|   ||.     :||                                ..|..|.:|:
Human    69 TPMTPENFT---SCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130

  Fly   104 VNEEEKIRTDFNDMALEFFNAEAYSLNYLN-PEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSS 167
            ..:....|.::..:..:::::|..::::|. .|::.||:|.|::..|...:.||......:.|:.
Human   131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTR 195

  Fly   168 VILVNSLFFRAKWNKIFPQQLTQIDDFWINPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFER 232
            ::|||:::|:.||...|.::|..:..|.:|..||..|.||....:...|..:.||:|||:||: .
Human   196 MVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPY-A 259

  Fly   233 SNLTMMIILPTAI----DGLPELEEKLGQLDMNEVAAKSLM--KEVDVTIPKFRIECTVDLKVPL 291
            .:::|.::||..|    .||..||.::....:|:..:|..|  .||:|.||:|::|...:|:..|
Human   260 GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSIL 324

  Fly   292 QKMGINSVFDAGQADLS------DLFEMKTPQKISEARHKVFLNVTEFGCEVA------------ 338
            :.||:...|:.|:|:.|      |||       :||..|:..::|.|.|.|.|
Human   325 RSMGMEDAFNKGRANFSGMSERNDLF-------LSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTG 382

  Fly   339 ---PEAEVQPEVLKKNPDRKFFKADRPFVFAIRDR--KNVYFVGHFVKP 382
               |:                |.||.||:|.|..:  ..:.|.|.|..|
Human   383 HGGPQ----------------FVADHPFLFLIMHKITNCILFFGRFSSP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	110/427 (26%)
SERPINB2	NP_001137290.1	PAI-2	4..415	CDD:239013	112/437 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920