Protein Alignment Spn47C and SERPINE1

DIOPT Version :9

• Sequence 1: NP_001163116.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001373389.1
• Gene: SERPINE1 / 5054
• HGNCID: 8583
• Length: 492
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 93/387 - (24%)
• Similarity: 159/387 - (41%)
• Gaps: 74/387 - (19%)

  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRS------------------- 63
            |...:|:.:.......|::.||.|..|.:.::.:..||::..::::
Human    38 FGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLY 102

  Fly    64 KLILGVSNKSEVAKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYS 128
            |.::|..||.|:      |.||               .::|..:.|:...|.......|.:....
Human   103 KELMGPWNKDEI------STTD---------------AIFVQRDLKLVQGFMPHFFRLFRSTVKQ 146

  Fly   129 LNYLNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDD 193
            :::...|.:...:|.|::.||...:.||......:..:.::|||:|:|..:|...||...|....
Human   147 VDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRL 211

  Fly   194 FWINPRQRMEVSMMRQIGQFRYGESKKLKS---QILQLPFERSNLTMMIILPTAIDGLPELEEKL 255
            |..:....:.|.||.|..:|.|.|......   .||:||:....|:|.|..|.      |.|..|
Human   212 FHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPY------EKEVPL 270

  Fly   256 GQLDMNEVAA------KSLMKEVD--VTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFE 312
            ..| .|.::|      |..|..:.  :.:|||.:|..|||:.||:.:|:..:|...|||.:.|.:
Human   271 SAL-TNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD 334

  Fly   313 MKTPQKISEARHKVFLNVTEFG------CEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIR 368
            .: |..:::|..||.:.|.|.|      ..|...|.:.||.:         ..||||:|.:|
Human   335 QE-PLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEI---------IMDRPFLFVVR 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	93/387 (24%)
SERPINE1	NP_001373389.1	serpinE1_PAI-1	29..393	CDD:381007	93/387 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020