DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and serpinc1

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001008153.1	Gene:	serpinc1 / 493515	XenbaseID:	XB-GENE-975782	Length:	456	Species:	Xenopus tropicalis

Alignment Length:	389	Identity:	105/389 - (26%)
Similarity:	181/389 - (46%)	Gaps:	26/389 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LSASPIVFARNLFRALNDEVPPV-NMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSE 74
            ||.:...||...::.|.|..... |:.:||.....|.|:..:||...:..||..  :......||
Frog    74 LSQANAKFAIAFYKNLADSKQNTENIFMSPLSISQAFTMAKLGACNNTLKELME--VFYFDTISE 136

  Fly    75 VAKQHAESWTDECSC-----AKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYL-N 133
            .|......:..:.:|     |.|...|..|.||:..:.......:.|::...:.|:...||:. .
Frog   137 RASDQIHYFFAKLNCRLFRKANKSSELVSVNRLFGEKSLTFNETYQDISELVYGAKLLPLNFKEK 201

  Fly   134 PEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWINP 198
            ||.|.:.:|.|:...|...:.::....|...|:.::|:|:::|:..|...|..:.|:::.|:.:.
Frog   202 PELSREIINNWVSDKTEKRITDVIPVGVITPDTVLVLINAIYFKGLWKSKFNSENTKMEQFYPDE 266

  Fly   199 RQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDMNEV 263
            ......:.|.|.|.|||...|....|:|:||::..::||:::||:....|.::|:.|....:...
Frog   267 SNHCLAATMYQEGIFRYSSFKDDGVQVLELPYKGDDITMVLVLPSPETPLMKVEQNLTLEKLGNW 331

  Fly   264 AAKSLMKEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADL--------SDLFEMKTPQKIS 320
            ..||...::.|.:|:||:|.:..:|..||:||:..:||...|.|        :||:       :|
Frog   332 LQKSRELQLSVYLPRFRVEDSFSVKEKLQQMGLVDLFDPNSAKLPGIVAGGRTDLY-------VS 389

  Fly   321 EARHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIRD--RKNVYFVGHFVKP 382
            :|.||.||.|.|.|.|.|....|.......|.:|..|:|:|||:..||:  ..:|.|:|....|
Frog   390 DAFHKAFLEVNEEGSEAAASTAVILTGRSLNLNRITFRANRPFLVFIREVAINSVLFMGRVANP 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	102/377 (27%)
serpinc1	NP_001008153.1	serpinC1_AT3	61..455	CDD:381002	105/389 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110