DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and serpine2

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_956478.1	Gene:	serpine2 / 393153	ZFINID:	ZDB-GENE-040426-848	Length:	395	Species:	Danio rerio

Alignment Length:	367	Identity:	98/367 - (26%)
Similarity:	174/367 - (47%)	Gaps:	38/367 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 NMMVSPAGARSAMTLVFMGAGGKSADELRSKL---------ILGVSNKSEVAKQHAESWTDECSC 89
            |:::||.|..|.:.::..||.|.:..:|.:.|         :|...:||...|.:|:..|
Zfish    49 NVLLSPHGVASVLGMLLPGAHGDTRRQLLNGLKYKKNGPYKMLRKLHKSLTTKSNADIVT----- 108

  Fly    90 AKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNPEDSVKKVNKWLEKHTFYTVR 154
                    :...|:.||...::.||.....|.|..|::|::|.:||.:.:.:|.|::..|...:.
Zfish   109 --------IANALFPNEGFSMKEDFLSANRENFLCESHSVDYSDPEAAAQSINDWVKNSTKGQIP 165

  Fly   155 NLFTPEVFNSD-SSVILVNSLFFRAKWNKIFPQQLTQIDDFWINPRQRMEVSMMRQIGQFRYGES 218
            ::.|.::|::. :.::.|||:||:..|...|..|.|:...|........:|.||.|:..|..|::
Zfish   166 SVVTADMFDTALTRLVAVNSIFFKGLWKSRFQPQSTKPRSFTAGDGNTYKVPMMSQLSVFNMGQA 230

  Fly   219 KKLKSQ---ILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDMNEVAA-KSLM--KEVDVTIP 277
            .....|   :::||:..::::|.|.|||. |..| |...|..:..|.:.: ..||  :.:.:.:|
Zfish   231 STPDGQKYIVIELPYHGNSMSMFIALPTE-DSTP-LSSILPHISTNTIQSWTKLMNPRRMRLLMP 293

  Fly   278 KFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEARHKVFLNVTEFGCEVAPEAE 342
            ||.:|..:||:.||:.:||..:||..:||...|.....  .:|:|..|..:.|.|.|.:.:....
Zfish   294 KFTVEQELDLETPLKALGIKDIFDQNKADFRHLSSESI--YVSKALQKAKIEVNEDGTKASATTS 356

  Fly   343 VQPEVLKKNPDRKFFKADRPFVFAIRDRKN--VYFVGHFVKP 382
            |   :|.......:...||||:|.||...:  :.|.|...||
Zfish   357 V---ILHARSSPPWVTVDRPFLFLIRHNSSGTILFAGQINKP 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	96/362 (27%)
serpine2	NP_956478.1	PAI-1_nexin-1	26..395	CDD:239006	96/365 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020