DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpina11

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_955018.2	Gene:	Serpina11 / 380780	MGIID:	2685741	Length:	427	Species:	Mus musculus

Alignment Length:	401	Identity:	99/401 - (24%)
Similarity:	192/401 - (47%)	Gaps:	33/401 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASGGTTAPSLSASPIV---------FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKS 57
            ||...:..||..:|..         ||..|::.|.:||.. |::.||....|::.|:.:||...:
Mouse    37 ASQPASHQSLEPAPAYHKVTPTITNFALRLYKQLAEEVAG-NILFSPVSLSSSLALLSLGAHADT 100

  Fly    58 ADELRSKLILGVSNKSEVAKQHA--ESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALE 120
            ..::...|...:: ::..|..|.  :|...........:.|:|...|:::.:.|.:..|.|.|.|
Mouse   101 QTQILESLGFNLT-ETPAADVHRGFQSLLHTLDLPSPKLELKLGHFLFLDRQLKPQQRFLDSAKE 164

  Fly   121 FFNAEAYSLNYLNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFP 185
            .:.|.|:|.|:.....:.:::|..:.|.|:..|.... || |:.|:.::|:|.:||:||....|.
Mouse   165 LYGALAFSANFTEAAATGQQINDLVRKQTYGQVVGCL-PE-FSHDTLMVLLNYIFFKAKCKHPFD 227

  Fly   186 Q-QLTQIDDFWINPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLP 249
            : |..:.:.|.::.|..:.:.||||....|:...::....:||:.:..:.| ::::||.. ..:.
Mouse   228 RYQTRKQESFSLDQRTPLRIPMMRQKEMHRFLYDQEASCTVLQIEYSGTAL-LLLVLPDP-GKMQ 290

  Fly   250 ELEEKLGQLDMNEVAAKSLMKEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEM- 313
            ::|..|....:.....:.|...:|:.:|:|.|..|.:|:..|..:|:.::||. :||||.:...
Mouse   291 QVEAALQPETLRRWGQRFLPSLLDLHLPRFSISATYNLEEILPLIGLGNLFDM-EADLSGIMGQL 354

  Fly   314 -KTPQKISEARHKVFLNVTEFGCEVAPEAEV--QPEVLKKN--PDRKFFKADRPFVFAIRD--RK 371
             ||..::|   ||..:::.|.|.|.|..:.:  ||..|...  |...:   :|||:..:.:  .:
Mouse   355 NKTVSRVS---HKAIVDMNEKGTEAAAASGLLSQPPALNMTSAPQAHY---NRPFLLLLWEVTTQ 413

  Fly   372 NVYFVGHFVKP 382
            ::.|:|..|.|
Mouse   414 SLLFLGKVVNP 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	92/371 (25%)
Serpina11	NP_955018.2	SERPIN	58..421	CDD:294093	92/375 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100