DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn47C and SERPINA9

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_783866.3	Gene:	SERPINA9 / 327657	HGNCID:	15995	Length:	417	Species:	Homo sapiens

Alignment Length:	371	Identity:	94/371 - (25%)
Similarity:	185/371 - (49%)	Gaps:	13/371 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEVA-KQHAE 81
            ||..|:|.|..|.|..|:..||....:::.::.:||...:..::...|...:::..|.| .|..:
Human    51 FAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQ 115

  Fly    82 SWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNPEDSVKKVNKWLE 146
            ......:...|.:.|::.:.|:|.:|.:::.:|.......:.||.:|.::.||..:..::|..::
Human   116 HLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVK 180

  Fly   147 KHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQID-DFWINPRQRMEVSMMRQI 210
            |.|...|.::.  :..:..::::|||.:||:|||.|.|..:.|:.: .|.:..:..:.|.||.|.
Human   181 KKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQK 243

  Fly   211 GQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDMNEVAAKSLMKEVDVT 275
            .||.:|...:|...:||:.: :.:.....:||:. ..:.:||:.|....:.:.:.....:.::|.
Human   244 EQFAFGVDTELNCFVLQMDY-KGDAVAFFVLPSK-GKMRQLEQALSARTLRKWSHSLQKRWIEVF 306

  Fly   276 IPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEARHKVFLNVTEFGCEVAPE 340
            ||:|.|..:.:|:..|.||||.:|||. .||.|.:.:..:.| :|:|.||..|:|:|.|.| |..
Human   307 IPRFSISASYNLETILPKMGIQNVFDK-NADFSGIAKRDSLQ-VSKATHKAVLDVSEEGTE-ATA 368

  Fly   341 AEVQPEVLKKNPDRKFFKA--DRPFVFAIRDR--KNVYFVGHFVKP 382
            |.....:::......:|..  :|.|:..|.::  ..:.|:|....|
Human   369 ATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	93/366 (25%)
SERPINA9	NP_783866.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020