DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpinb13

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001100638.1	Gene:	Serpinb13 / 304690	RGDID:	1304661	Length:	389	Species:	Rattus norvegicus

Alignment Length:	391	Identity:	111/391 - (28%)
Similarity:	196/391 - (50%)	Gaps:	22/391 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SLSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLI----LGVS 70
            |||.:...|..:||:.|| :....|:..||.|..:|:.::.:|..|.:|.||:..|.    .|.|
  Rat     3 SLSTATTHFLFDLFKELN-KTSDGNVFFSPLGISTAIGMILLGTQGATASELQKVLYSEQGTGSS 66

  Fly    71 ---------NKSEVAKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEA 126
                     .|:|......:....|.|...|...|.:..|||..........:.|...::::|..
  Rat    67 RLKSEEKEIEKTEEIHHQFQKLLTEISKPTKDYDLIISNRLYGERTYLFLQKYIDYVEKYYHASL 131

  Fly   127 YSLNYLNPED-SVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQ 190
            ..::::|..| |.||:|.|:|..|...|::||.....||.:.::|:|:::|:..|::.|.::.|:
  Rat   132 EPVDFVNAADESRKKINSWVESQTNEKVKDLFPEGSLNSSTKLVLINTVYFKGLWDREFKKEHTK 196

  Fly   191 IDDFWINPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKL 255
            .:|||:|......|.||.|...|.:...:.|:::|:.:|::.|:.:|.::||..||||.::.:||
  Rat   197 EEDFWLNKNISKPVQMMAQCSSFSFTLLEDLQAKIVGIPYKNSDFSMFVLLPNDIDGLEKIIDKL 261

  Fly   256 GQLDMNEVAAKSLMKE--VDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQK 318
            ....:.|..:...:|:  ||:.:|:.::|.|.||:..|:.:||:|.| :..||.|.: ...:..:
  Rat   262 SPEKLVEWTSPGQLKQRKVDLRLPRLKVEETYDLQPTLEAVGIHSAF-SEHADYSGM-SAHSGLQ 324

  Fly   319 ISEARHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIRDRK--NVYFVGHFVK 381
            .....|:.||.|||.|.|......|..:||.. ...:....:.||:|.:|.|:  ::.|.|.|..
  Rat   325 TQNFLHRSFLVVTEEGVEATAGTGVGFKVLSA-ASCELVHCNHPFLFFVRHRESDSILFFGRFSS 388

  Fly   382 P 382
            |
  Rat   389 P 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	106/378 (28%)
Serpinb13	NP_001100638.1	SERPIN	4..389	CDD:294093	109/388 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820