DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serping1

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_954524.1	Gene:	Serping1 / 295703	RGDID:	735225	Length:	504	Species:	Rattus norvegicus

Alignment Length:	412	Identity:	90/412 - (21%)
Similarity:	182/412 - (44%)	Gaps:	94/412 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SLSASPIVFARNLFRALN-DEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKS 73
            :||.:...|:..|:.|.: .:....||..||....|.:|.|.:|||..:...|...|
  Rat   146 TLSEALTDFSVKLYHAFSATKKAETNMAFSPFSIASLLTQVLLGAGDSTKSNLEDIL-------- 202

  Fly    74 EVAKQHAESWTDECSC--------AKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLN 130
                    |:..:.:|        :.|||.  .|::::.:.:..||..:.:.:|..:.:   |..
  Rat   203 --------SYPKDFACVHQTLKAFSSKGVT--SVSQIFHSPDLAIRDTYVNASLSLYGS---SPR 254

  Fly   131 YLNPED--SVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDD 193
            .|.|:.  ::|.:|.|:.::|.:.:..|.  :...||:.::|:|:::..|||.|.|.|:......
  Rat   255 VLGPDGDANLKLINTWVAENTNHKINELL--DSLPSDTRLVLLNAVYLSAKWKKTFEQKKMMASF 317

  Fly   194 FWINPRQRMEVSMMRQIGQFRYGESKK----------LKSQILQLPFERSNLTMMIILP-TAIDG 247
            .:.|  ..::|.|:         .|||          ||:::.||.... ||:.:|::| :....
  Rat   318 LYKN--SMIKVPML---------SSKKYPLALFNDQTLKAKVGQLQLSH-NLSFVIMVPQSPTHQ 370

  Fly   248 LPELEEKLGQLDMNEVAAKSLMKEVD--------VTIPKFRIECTVDLKVPLQKMGINSVFD--- 301
            |.::|:.|     |....|:::|:::        |.:|:.:::.:.|:...::|:   ..||
  Rat   371 LEDMEKAL-----NPTVFKAILKKLELSKFQPTYVMMPRIKVKSSQDMLSIMEKL---EFFDFTY 427

  Fly   302 ----AGQADLSDLFEMKTPQKISEARHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRP 362
                .|..:..||       ::|..:|:..|.:||.|.|.|..:.:.   :.:|  ...|:..:|
  Rat   428 DLNLCGLTEDPDL-------QVSSMKHETVLELTETGVEAAAASTIS---VARN--LLIFEVQQP 480

  Fly   363 FVFAIRDRKNVY--FVGHFVKP 382
            |:|.:.|:::.:  |:|....|
  Rat   481 FLFLLWDQRHKFPVFMGRVYDP 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	87/399 (22%)
Serping1	NP_954524.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..75
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..132
		SERPIN	150..499	CDD:294093	87/403 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100