DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpinf1

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_808788.1	Gene:	Serpinf1 / 287526	RGDID:	631369	Length:	418	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	84/407 - (20%)
Similarity:	174/407 - (42%)	Gaps:	42/407 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASGGTTAPSLSASPIV--------------------FARNLFRALNDEVPPVNMMVSPAGARSAM 46
            :|..:.||..:..|:|                    |..:|:|..:..|...|:::||....:|:
  Rat    25 SSQDSPAPDSTGEPVVEEDDPFFKAPVNKLAAAVSNFGYDLYRLRSGAVSTGNILLSPLSVATAL 89

  Fly    47 TLVFMGAGGKSADELRSKLILGVSNKSEVAKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIR 111
            :.:.:||..::...:...|...:.|..::...:.|......:..|.   .:..:|:....:.:::
  Rat    90 SALSLGAEQRTESVIHRALYYDLINNPDIHSTYKELLASVTAPEKN---FKSASRIVFERKLRVK 151

  Fly   112 TDFNDMALEFFNAEAYSLNYLNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFF 176
            :.|.....:.:......|.. ||...::::|.|::......:..  :.....|..|::|:...:|
  Rat   152 SSFVAPLEKSYGTRPRILTG-NPRIDLQEINNWVQAQMKGKIAR--STREMPSALSILLLGVAYF 213

  Fly   177 RAKWNKIFPQQLTQIDDFWINPRQRMEVSMM---RQIGQFRYGESKKLKSQILQLPFERSNLTMM 238
            :.:|...|..:.|.:.||.::..:.:.|.||   :.|  .|||....|..:|.|||...| ::::
  Rat   214 KGQWATKFDSRKTTLQDFHLDEDRTVRVPMMSDPKAI--LRYGLDSDLNCKIAQLPLTGS-MSII 275

  Fly   239 IILP-TAIDGLPELEEKLGQLDMNEVAAKSLMKEVDVTIPKFRIECTVDLKVPLQKMGINSVFDA 302
            ..|| |....|..:||.|....::::..:....:..:|:||.::....|:...||.|.:.|:|::
  Rat   276 FFLPLTVTQNLTMIEESLTSEFVHDIDRELKTIQAVLTVPKLKLSYEGDVTNSLQDMKLQSLFES 340

  Fly   303 GQADLSDLFEMKTPQKISEARHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAI 367
              .|.|.:  ...|.|:::..|:......|.|...:...::||..|....|   :..:|||:|.:
  Rat   341 --PDFSKI--TGKPVKLTQVEHRAAFEWNEEGAGTSSNPDLQPVRLTFPLD---YHLNRPFIFVL 398

  Fly   368 RDRKN--VYFVGHFVKP 382
            ||...  :.|:|..:.|
  Rat   399 RDTDTGALLFIGRILDP 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	78/366 (21%)
Serpinf1	NP_808788.1	PEDF	40..415	CDD:239007	79/390 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100