Protein Alignment Spn47C and Serpinb1b

DIOPT Version :10

• Sequence 1: NP_610633.1
• Gene: Spn47C / 36163
• FlyBaseID: FBgn0033574
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_766640.1
• Gene: Serpinb1b / 282663
• MGIID: 2445361
• Length: 382
• Species: Mus musculus
• Alignment Length: 399
• Identity: 114/399 - (28%)
• Similarity: 199/399 - (49%)
• Gaps: 47/399 - (11%)

  Fly    11 LSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEV 75
            ||::..:|...||..|.:..|..|:..||....|::.:||:||.|.:|.:|...|
Mouse     4 LSSANTLFTLELFHTLKESSPTGNIFFSPFSISSSLAMVFLGAKGSTAAQLSKTL---------- 58

  Fly    76 AKQHAESWTDECSC--------AKKGVA--LRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLN 130
               |.:|..|..||        :|.|.:  |:|..|||..:......:|.....:.::|:..:::
Mouse    59 ---HFDSVEDIHSCFQSLTAEVSKLGASHTLKLANRLYGEKTYNFLPEFLASTQKMYSADLAAVD 120

  Fly   131 YLN-PEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDF 194
            :.: .||:.|::|:|::..|...:..|....|.:|.:.::|||:::|:..|.:.|..:.|....|
Mouse   121 FQHASEDARKEINQWVKGQTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPF 185

  Fly   195 WINPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAID----GLPELEEKL 255
            .:|.:....|.||.|..:|.:|....||.::|::|::...|:|:|:||..|:    ||.::||:|
Mouse   186 RLNKKDTKTVKMMYQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLKKIEEQL 250

  Fly   256 GQLDMNEVAAKSLMKEVD--VTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLS------DLFE 312
            ....::|......::.:|  |.:|:|::|.:..|...|..:|:..:|.:|:||||      |||
Mouse   251 TLGKLHEWTKHENLRNIDVHVKLPRFKMEESYILNSNLCCLGVQDLFSSGKADLSGMSGSRDLF- 314

  Fly   313 MKTPQKISEARHKVFLNVTEFGCEVAPEAEVQPEVL-KKNP-DRKFFKADRPFVFAIRDR--KNV 373
                  :|:..||.|::|.|.|.|.|.......:|| :|.| .::.|..|.||:|.||..  .|:
Mouse   315 ------VSKIVHKSFVDVNEQGTEAAAATGGIIQVLCEKMPTPQEVFTVDHPFLFFIRHNPTANM 373

  Fly   374 YFVGHFVKP 382
            .|.|....|
Mouse   374 IFFGRVCSP 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_610633.1	serpin42Dd-like_insects	13..382	CDD:381070	111/395 (28%)
Serpinb1b	NP_766640.1	serpinB1_LEI	1..382	CDD:381028	113/397 (28%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	352..382		10/29 (34%)