DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpinf2

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_032904.1	Gene:	Serpinf2 / 18816	MGIID:	107173	Length:	491	Species:	Mus musculus

Alignment Length:	387	Identity:	90/387 - (23%)
Similarity:	170/387 - (43%)	Gaps:	47/387 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEV 75
            |:.:.:.|..:||..:.......|:::||.....|::.:.:||..::...|...|.:...
Mouse    82 LAQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMNTG----- 141

  Fly    76 AKQHAESWTDECSCAKKGVA----------LRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLN 130
                        ||....::          :||..|:|:.:...|:.||.:.:...|.|:...|.
Mouse   142 ------------SCLPHLLSHFYQNLGPGTIRLAARIYLQKGFPIKDDFLEQSERLFGAKPVKLT 194

  Fly   131 YLNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSV-ILVNSLFFRAKWNKIFPQQLTQIDDF 194
            ....|| :..:|:|:::.|...:.: |..|:  .||:| :|:|::.|...|...|...|||.|.|
Mouse   195 GKQEED-LANINQWVKEATEGKIED-FLSEL--PDSTVLLLLNAIHFHGFWRTKFDPSLTQKDFF 255

  Fly   195 WINPRQRMEVSMMRQIG-QFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQL 258
            .::.|..:.|.||..:. ..|:...::.:.|:...|| ::|::.::::||..:.  .:.|.|..|
Mouse   256 HLDERFTVSVDMMHAVSYPLRWFLLEQPEIQVAHFPF-KNNMSFVVVMPTYFEW--NVSEVLANL 317

  Fly   259 DMNEVAAKSLM-KEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEA 322
            ..:.:...||. :...|.:||..::..:||...|.::|:..:|..  .||..:.|...  .:|..
Mouse   318 TWDTLYHPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQELFQG--PDLRGISEQNL--VVSSV 378

  Fly   323 RHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAI-RDRKNV-YFVGHFVKP 382
            :|:..:.::|.|.|.|....|....:..:.    |..:|||:|.| .|...| .|||....|
Mouse   379 QHQSTMELSEAGVEAAAATSVAMNRMSLSS----FTVNRPFLFFIMEDTIGVPLFVGSVRNP 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	88/375 (23%)
Serpinf2	NP_032904.1	alpha2AP	82..433	CDD:239008	89/382 (23%)
Serpinf2	NP_032904.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..491
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100