DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpinb2

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001167641.1	Gene:	Serpinb2 / 18788	MGIID:	97609	Length:	415	Species:	Mus musculus

Alignment Length:	423	Identity:	110/423 - (26%)
Similarity:	200/423 - (47%)	Gaps:	62/423 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKL------ILGV 69
            ||.:..:||.||.:.:.......|:.:||....|.:.:|.:||||.:..::...|      ..|:
Mouse     4 LSMANTMFALNLLKQIEKSNSTQNIFISPWSISSTLAIVLLGAGGNTEQQMAKVLQFNEIGSYGI 68

  Fly    70 SNKS-------EVAKQ-HAESWTDECSCAKKG--------------------VALRLVTRLYVNE 106
            :.::       :.|:| ..|::......|:.|                    ..|....:|:..:
Mouse    69 TTRNPENFSGCDFAQQIQKENYPSAILQAQAGDKIHSAFSSLSSTINTPQGDYLLESANKLFGEK 133

  Fly   107 EEKIRTDFNDMALEFFNAEAYSLNYLN-PEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVIL 170
            ..:.:.::..::.::::.|..::::|. .|::.:|:|.|::..|...:.||......:.|:.::|
Mouse   134 SARFKEEYIQLSKKYYSTEPEAVDFLECAEEAREKINSWVKTQTKGEIPNLLPEGSVDEDTKMVL 198

  Fly   171 VNSLFFRAKWNKIFPQQLTQIDDFWINPRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSNL 235
            ||:::|:.||...|.::|..:..|.:|..:.:.|.||....:...|..|.||:|||:|| ...|:
Mouse   199 VNAVYFKGKWKTPFEKKLNGLYPFRVNSHESIPVQMMFLHAKLNIGYIKDLKTQILELP-HTGNI 262

  Fly   236 TMMIILPTAID----GLPELEEKLGQLDMNEVAAKSLMKEVDVT--IPKFRIECTVDLKVPLQKM 294
            :|:::||..|:    ||..||.::...:.|:..:|..:.|.||.  ||||::..:.:||..||.|
Mouse   263 SMLLLLPDEIEDASTGLELLESEINFANFNKWISKDTLDEDDVVVYIPKFKLAQSYELKSILQSM 327

  Fly   295 GINSVFDAGQADLS------DLFEMKTPQKISEARHKVFLNVTEFGCEVA--PEAEVQPEVLKKN 351
            |:...|:.|:|:.|      |||       :||..|:..::|||.|...|  ..|.:........
Mouse   328 GMEDAFNKGKANFSGMSERNDLF-------LSEVFHQASVDVTEEGTVAAGGTGAVMTGRTGHGG 385

  Fly   352 PDRKFFKADRPFVFAIRDR--KNVYFVGHFVKP 382
            |.   |.||.||:|.|.|:  ..:.|||.|..|
Mouse   386 PQ---FVADHPFLFFIMDKITHTILFVGRFSSP 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	106/411 (26%)
Serpinb2	NP_001167641.1	SERPIN	4..415	CDD:294093	109/421 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920