DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpina3c

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_011242304.1	Gene:	Serpina3c / 16625	MGIID:	102848	Length:	436	Species:	Mus musculus

Alignment Length:	401	Identity:	98/401 - (24%)
Similarity:	182/401 - (45%)	Gaps:	48/401 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GTTAPSLSASPI--VFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLIL 67
            ||...||:.:.|  .||.:|::.|..:.|..|::.||....:|:.:|.:||.|.:.:|:...|..
Mouse    58 GTQLDSLTLASINTDFAFSLYKKLALKNPDTNIVFSPLSISAALAIVSLGAKGNTLEEILEGLNF 122

  Fly    68 GVSNKSEV-AKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNY 131
            .::...|. ..|.........|...:.|.:...:.|:|.:..:|..:|.:.|...:.|||::.::
Mouse   123 NLTETPEADIHQGFGHLLQRLSHPGEQVQISTGSALFVEKHLQILAEFQEKARALYQAEAFTADF 187

  Fly   132 LNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWI 196
            ..|.::.|.:|.::...|...::.|.:.  .::|:.::|||.::|:.||...|..:.|...:|::
Mouse   188 QQPLEATKLINDYVSNQTQRKIKGLISD--LDTDTLMVLVNYIYFKGKWKMPFNPRDTFESEFYL 250

  Fly   197 NPRQRMEVSMMR-QIGQFRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDM 260
            :.::.::|.||: :.....|...::|...:::|.: :.|.:.:.|||             .|..|
Mouse   251 DVKRSVKVPMMKIKTLTTPYFRDEELSCTVVELKY-KGNASALFILP-------------DQGRM 301

  Fly   261 NEVAAKSLMKEV--------------DVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLF 311
            .:|.| ||..|.              ::.:|||.|.....||..|.::||..:| :.|||||.:
Mouse   302 QQVEA-SLQPETLRKWKNSLRPRKMGELYLPKFSISTDYSLKNILPELGIKEIF-SKQADLSGI- 363

  Fly   312 EMKTPQK---ISEARHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAI--RDRK 371
               |..|   :|:..||..|:|.|.|.|......|...:|.:.....|   :|.|:..|  .|.:
Mouse   364 ---TGTKDLIVSQMVHKAVLDVAETGTEGVAATGVNFRILSRRTSLWF---NRTFLMVISHTDVQ 422

  Fly   372 NVYFVGHFVKP 382
            ...|:.....|
Mouse   423 TTLFIAKITHP 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	92/381 (24%)
Serpina3c	XP_011242304.1	serpinA3_A1AC	56..434	CDD:381019	98/401 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010