DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and Serpinb5

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_476449.2	Gene:	Serpinb5 / 116589	RGDID:	69342	Length:	375	Species:	Rattus norvegicus

Alignment Length:	374	Identity:	101/374 - (27%)
Similarity:	193/374 - (51%)	Gaps:	18/374 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEVAKQHAES 82
            ||..||:.|.::.|..|::.||....::::|..:||.|.:|:|:..  :|...|..:|.... ::
  Rat    11 FAVELFKQLCEKEPAGNILFSPICLSTSLSLAQVGAKGDTANEIGQ--VLHFENVKDVPFGF-QT 72

  Fly    83 WTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNP-EDSVKKVNKWLE 146
            .|.:.:......:|:|:.|||:::...:.|:|.......:..|..::::.:. |::..::|..::
  Rat    73 ITSDVNKLSSFYSLKLIKRLYIDKSLNLSTEFISSTKRPYANELETVDFKDKLEETKGQINSSIK 137

  Fly   147 KHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWINPRQRMEVSMMRQIG 211
            :.|.....::......:..:.:::||:.:|..||.|.||:..|:...|.||......|.||....
  Rat   138 ELTDGHFEDILPENSISDQTKILVVNAAYFVGKWMKKFPESETKECPFRINKTDTKPVQMMNLEA 202

  Fly   212 QFRYGESKKLKSQILQLPFERSNLTMMIILPTAID----GLPELEEKLGQLDMNEVAAKSLM--K 270
            .|..|....:..:|::|||:..:|:|:|:||..::    ||.::|::|....:.:....|.|  .
  Rat   203 TFCLGNIDDINCKIIELPFQNKHLSMLIVLPKDVEDESTGLEKIEKQLNPETLLQWTNPSTMANA 267

  Fly   271 EVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEARHKVFLNVTEFGC 335
            :|.:::|||::|..:|.|..|:.:|:.|:|:...:|.|.:.|.| ...:|...|:|.|.:||.|
  Rat   268 KVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSDFSGMSETK-GVSVSNVIHRVCLEITEDG- 330

  Fly   336 EVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIRDRK--NVYFVGHFVKP 382
              ....||....:.::.|.  ||||.||:|.:|..|  |:.|:|.|..|
  Rat   331 --GDSIEVPGSRILQHKDE--FKADHPFLFIVRHNKTRNIVFLGKFSSP 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	99/369 (27%)
Serpinb5	NP_476449.2	serpinB5_maspin	1..375	CDD:381013	100/372 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920