DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and LOC100909605

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_006240581.2	Gene:	LOC100909605 / 100909605	RGDID:	6502633	Length:	410	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	98/379 - (25%)
Similarity:	175/379 - (46%)	Gaps:	41/379 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SLSASPIVFARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSE 74
            :||:....||.:|::.|..:.|..|::.|.....:|:.|:.:||...:..|:...|...::...|
  Rat    36 TLSSCNTDFAFSLYKELVLKNPDKNIVFSSFSISTALVLLSLGAKNNTLKEILEGLKFNLTETPE 100

  Fly    75 V-AKQHAESWTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNPEDSV 138
            . ..|..|......:.....|.:...:.|::.:..:|..:|.:.|...:.|||:|.::..|.::.
  Rat   101 AEIHQGYEHLLQRLNLPGDQVQISTGSALFIKKHLQILAEFQEKARALYQAEAFSTDFQQPHEAK 165

  Fly   139 KKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWINPRQRME 203
            |.:|.::.|.|...::.|.:  |.:..:|::|||.::|:.||...|....|...:|:::.::.::
  Rat   166 KLINDYVRKQTQGKIKELIS--VLDKKTSMVLVNYIYFKGKWKMPFDPHDTFQSEFYLDEKKSVK 228

  Fly   204 VSMMRQIGQFR--YGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELEEKLGQLDMNEVAAK 266
            |.||: |.:..  |...::|...:|:|.: ..|.:.:.|||             .|..|.:|.|
  Rat   229 VPMMK-IEKLTTPYFRDEELSCSVLELKY-TGNASALFILP-------------DQGRMQQVEA- 277

  Fly   267 SLMKEV--------------DVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQ 317
            ||..|.              ::.:|||.|...:.|...|.::||..|| :.|||||.:...| ..
  Rat   278 SLQPETLRRWKDTLRPRRIDELRMPKFSISTDMRLGDILPELGIREVF-SQQADLSRITGAK-DL 340

  Fly   318 KISEARHKVFLNVTEFGCEVAPEAEVQ--PEVLKKNPDRKFFKADRPFVFAIRD 369
            .:|:..||..|:|||.|.|.|....|:  |...|......:|  :|||:..|.|
  Rat   341 SVSQVVHKAVLDVTETGTEAAAATGVKIIPMCAKFYYVTMYF--NRPFLMIISD 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	96/371 (26%)
LOC100909605	XP_006240581.2	alpha-1-antitrypsin_like	41..404	CDD:239011	96/374 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010