DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn47C and serpine1

DIOPT Version :9

Sequence 1:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001108031.1	Gene:	serpine1 / 100136840	ZFINID:	ZDB-GENE-070912-60	Length:	384	Species:	Danio rerio

Alignment Length:	373	Identity:	82/373 - (21%)
Similarity:	154/373 - (41%)	Gaps:	45/373 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEVAKQHAES 82
            |...:|.......|..|:.:||.|..|.:.:..|||.|.:...|.||:...:..:.....|
Zfish    28 FGLQVFAEAVQSAPDRNLALSPYGIASVLGMAQMGAYGATLKLLASKMGYSLQERGMPKLQ---- 88

  Fly    83 WTDECSCAKKGVALRLVTRLYVNEE----------------EKIRTDFNDMALEFFNAEAYSLNY 131
                          ||:.|...:|:                ||:   |.....:.|.:..:.:::
Zfish    89 --------------RLLQRDLASEDGVEVASGVMVDRKIILEKV---FRRSLSKAFQSVPHQIDF 136

  Fly   132 LNPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWI 196
            ..||.:.:.:|.|...||...:.......|.:..:.::.:|:|.|...|...|..:.|:...|..
Zfish   137 SQPEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVWKTPFDPRNTREQLFHT 201

  Fly   197 NPRQRMEVSMMRQIGQFRYGE--SKK-LKSQILQLPFERSNLTMMIILPTAID-GLPELEEKLGQ 257
            .....:.|.||....:|.|||  ||. :...::::|:|..:::|:::.|...| .|..|.::|..
Zfish   202 VNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISMLLVTPFEKDVPLSALNKELSS 266

  Fly   258 LDMNEVAAKSLMKEVDVTIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEA 322
            ..:::...:.......::||:|.::..:|||..|.:||:..:|...:||.|.: ..:.|..:|:.
Zfish   267 SRIHQWRQEMRKISKQLSIPRFSMDTEIDLKSTLSRMGLGDIFSQSRADFSRI-TTEEPLCVSKV 330

  Fly   323 RHKVFLNVTEFGCEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIRDR 370
            ..:|.|.|.|.|.:   .:.....|:......:....||||.|.|:.:
Zfish   331 LQRVKLEVNEEGTK---GSSATAAVIYSRMAVEEITLDRPFFFLIQHK 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	82/373 (22%)
serpine1	NP_001108031.1	SERPIN	26..384	CDD:294093	82/373 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020