Protein Alignment polyph and SLC38A5

DIOPT Version :9

• Sequence 1: NP_610631.1
• Gene: polyph / 36161
• FlyBaseID: FBgn0033572
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: XP_005272751.2
• Gene: SLC38A5 / 92745
• HGNCID: 18070
• Length: 539
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 91/449 - (20%)
• Similarity: 173/449 - (38%)
• Gaps: 107/449 - (23%)

  Fly    54 SLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVPQVSMPEA 118
            :|...::|:|||.:..|...:|.:....:.:.:.:|.:||||||:.    |.....:.
Human   103 NLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLT----CAGIAGIR------- 156

  Fly   119 VRIAYEE-GPKWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEI----------GDHYI 172
               |||: |.:   .||.|...:...|:........:.||..:......:          ||.::
Human   157 ---AYEQLGQR---AFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFL 215

  Fly   173 ERYNERYYVLVACLLLLPLFMIRRLKYL-----VPLNLISNFL---LYAGFALIMYYLFN----- 224
            :  .....::|:.|::|||.:::.|.||     :.|..:..||   :|..|.|......|
Human   216 K--GNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAME 278

  Fly   225 -----GLPN--IN---DREMVTPPVEWIEFIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLN 279
                 |||:  :|   :.:|.|...:....:.|.||:......:|.:...:..| |...:..|.|
Human   279 SEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRP-SKRRMQAVAN 342

  Fly   280 LAV--LFILLSNMFFGI---IGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGF 339
            :::  :|.:     :|:   .||..|..:|.|.:.....|.:.|...:::.:...:.|:.|:..|
Human   343 VSIGAMFCM-----YGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLF 402

  Fly   340 ----VVITVMFSDYENSEPRGRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLN 400
                .:..::|.....|.||       ...:.|:.|.|...:.|.||.:..:..:.|:.|..:|.
Human   403 PIRRALQQLLFPGKAFSWPR-------HVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLI 460

  Fly   401 LLCPAL---------IDVFLNYNVGYGRLMWKLIRDILLILIGLIFGIVGCTVALMQLI 450
            .:.|::         ::.||:         |..|:              ||...:|.||
Human   461 FILPSIFYLRIVPSEVEPFLS---------WPKIQ--------------GCQAWIMALI 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	82/404 (20%)
SLC38A5	XP_005272751.2	SLC5-6-like_sbd	93..484	CDD:294310	85/421 (20%)
		SdaC	93..476	CDD:223884	82/404 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158635
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940