Protein Alignment polyph and AVT1

DIOPT Version :10

• Sequence 1: NP_610631.1
• Gene: polyph / 36161
• FlyBaseID: FBgn0033572
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_012534.1
• Gene: AVT1 / 853457
• SGDID: S000003761
• Length: 602
• Species: Saccharomyces cerevisiae
• Alignment Length: 433
• Identity: 83/433 - (19%)
• Similarity: 165/433 - (38%)
• Gaps: 90/433 - (20%)

  Fly    56 LKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVPQVSMPEAVR 120
            :..:||.|:||:||..:.:|:|:|..| :.:..|.|:    ..|::...|.......:|..:...
Yeast   218 INVLIGIGLLALPLGLKYAGWVIGLTM-LAIFALATF----CTAELLSRCLDTDPTLISYADLGY 277

  Fly   121 IAYEEGPKWINCFGRA----------AGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIERY 175
            .|:  |.|     |||          .|...:.|::||..|                 :....:|
Yeast   278 AAF--GTK-----GRALISALFTLDLLGSGVSLVILFGDSL-----------------NALFPQY 318

  Fly   176 NERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLY-----AGFALI-----MYYLFNGLPNIN 230
            :..::.:|:..::.|       ...:||:::||..|.     .|..|:     :|...:....:|
Yeast   319 STTFFKIVSFFIVTP-------PVFIPLSVLSNISLLGILSTTGTVLVICCCGLYKSSSPGSLVN 376

  Fly   231 DREMVTPPVEWIEFIAIAAFSLTAV-GSMLV---VEAHMAHPQSYLGLFGVLNLAVLFILLSNMF 291
            ..|....|:: ::.:.::...|:|. |...|   ::..|.||..:.   ..|........::::.
Yeast   377 PMETSMWPID-LKHLCLSIGLLSACWGGHAVFPNLKTDMRHPDKFK---DCLKTTYKITSVTDIG 437

  Fly   292 FGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFL----SYPLNGFVVITVM------- 345
            ..:||:..||:.|...||.|:...|...:|:...|::.:.:    ..|||...:::|:
Yeast   438 TAVIGFLMFGNLVKDEITKNVLLTEGYPKFVYGLISALMTIIPIAKTPLNARPIVSVLDVLMNVQ 502

  Fly   346 FSDYENSEPRGRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVF 410
            ..|...|..:.|....::...|:....:...:||..|....:....||.....:.|:.|...
Yeast   503 HIDEAASAIKRRAAKGLQVFNRIFINVVFVLIAINFPEFDKIIAFLGAGLCFTICLILPCWF--- 564

  Fly   411 LNYNVGYGRLM------WKLIRDILLILIGLIFGIVGCTVALM 447
                  |.||.      |:.:...:.|.|.::...:|...|::
Yeast   565 ------YLRLCKTTIKPWERVACHVTICISVVLSTLGVGAAII 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:444915	75/385 (19%)
AVT1	NP_012534.1	Aa_trans	206..601	CDD:279788	83/431 (19%)