DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment polyph and AVT5

DIOPT Version :9

Sequence 1:	NP_610631.1	Gene:	polyph / 36161	FlyBaseID:	FBgn0033572	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_009464.2	Gene:	AVT5 / 852189	SGDID:	S000000185	Length:	459	Species:	Saccharomyces cerevisiae

Alignment Length:	441	Identity:	88/441 - (19%)
Similarity:	162/441 - (36%)	Gaps:	107/441 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 ISLLKCVIGTGILAMPLAFRCSGFVMGT-------VMSILLMILLT-------YSIHLLIADMTE 103
            ::||....|.|:||||.||:..|.:.|.       :.|:..::|.|       .|.:...|.:|:
Yeast    10 LTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQ 74

  Fly   104 CCRRRRVPQVSMPEAVRIAYEEGPKWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFV--SKNFKE 166
            ...    |.:|:.....||       :.|||....::    ::.|..:...|..:|.  ..|...
Yeast    75 LIN----PSISVVFDFAIA-------VKCFGVGVSYL----IIVGDLVPQIVQSIFYRNDDNMSG 124

  Fly   167 IGDHYIERYNERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYLFNG------ 225
            ..:|::......|..|:...::.||...|.|..|...::|:...:.....||:|:..|.
Yeast   125 SQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVNRHQLERG 189

  Fly   226 -----LPNINDREMVTPPVEWIEFIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLNLAVLFI 285
                 :|: .|.:..:|    :..:.|..|:.|...:|..|........     |.|:....:|.
Yeast   190 QVYFMVPH-GDSQSHSP----LTTLPIFVFAYTCHHNMFSVINEQVDKS-----FKVIRRIPIFA 244

  Fly   286 LLSNMFFGII----GYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPL---------N 337
            ::...|..||    ||..||:|:..:| |.:..:.|.:...::.:...:.|::||         .
Yeast   245 IVLAYFLYIIIGGTGYMTFGENIVGNI-LTLYPNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVK 308

  Fly   338 GFVVITVMF---------------------------SDYENSEPRGRYRTLIEY-VVRLLFLFLT 374
            ..::....|                           :...|.||..|..:|... ::.|..|..:
Yeast   309 NIIIFIENFRKGKLYDNRASFIPLDNFNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFS 373

  Fly   375 GAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYNVGYGRLMWKLI 425
            ..:||.:.:||.:..:.||...::::.:.|.|.        ||     |||
Yeast   374 YLLAISITSLAKVLAIVGATGSTSISFILPGLF--------GY-----KLI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	82/421 (19%)
AVT5	NP_009464.2	Aa_trans	1..445	CDD:279788	88/441 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345995
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
TreeFam	0	0.000	Not matched by this tool.
	5	4.750