DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment polyph and slc38a8b

DIOPT Version :9

Sequence 1:	NP_610631.1	Gene:	polyph / 36161	FlyBaseID:	FBgn0033572	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	XP_021327596.1	Gene:	slc38a8b / 795255	ZFINID:	ZDB-GENE-121005-6	Length:	444	Species:	Danio rerio

Alignment Length:	472	Identity:	102/472 - (21%)
Similarity:	189/472 - (40%)	Gaps:	105/472 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RSVEVP-LTNCDAFISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTE 103
            |..:|| |.:..|...:||..:|.|:|..|.||..:|.| .|.:|:.::.|:.....|:|.....
Zfish    20 RGSDVPRLGSFGAIFIMLKSALGAGLLNFPWAFEKAGGV-NTAISVEMVSLVFLISGLVILGYAS 83

  Fly   104 CCRRRRVPQVSMPEAVRIAYEEGPKWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFK--- 165
            ...|    |.:..:.||          |..||..|.:.....||..|::...:||.|....:
Zfish    84 SISR----QNTYHDVVR----------NVCGRRIGHLCEICFVFNLFMISVAFLVVVQDQLEKLC 134

  Fly   166 -------------EIGDHYIERYNERYYVLVACL-LLLPLFMIRRL---KYLVPLNLISNFLLYA 213
                         |:..|:...|  |:.:...|| ::|||.:.:.:   ||...:..::  ..|.
Zfish   135 LSLYETVTGNTEAEMPHHWYTDY--RFALSFMCLIIILPLSIPKEIGIQKYTSVMGTLA--ATYL 195

  Fly   214 GFALI-MYYL------------FNGLPNINDREMVTPPVEWIEFIAIAAFSLTAVGSMLVVEAHM 265
            ..|:| .|||            ..||.:......|.|.:         .|......:.:.:.:.|
Zfish   196 SVAVIAKYYLKDTHTADLTPEHSQGLGSWASMFSVVPTI---------CFGFQCHEASIAIYSSM 251

  Fly   266 AHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGI 330
            .:.:....:| :...:::|.||.....|:.|:..||..|.:.|.::.|.::::....::.....|
Zfish   252 ENKKITHWVF-ISVTSMIFCLLIYTLTGVFGFLTFGRKVASDILMSYPGNDVVMIIARLLFGISI 315

  Fly   331 FLSYP----LNGFVVITVMFSDYENSEPRGRYRTLI--------EYVVRLLFLFLTGAVAIGVPN 383
            ...||    |...|::|.:...:|.       ||::        ..::.:|::.:|..:||.||:
Zfish   316 VTIYPIILLLGRSVILTQILRFWER-------RTIMTPVFEGRCRLILTILWITVTLLIAIFVPD 373

  Fly   384 LAALTELEGAFSLSNLNLLCPALIDVF------LNYNV-----GYGRLMWKLIRDILLILIG-LI 436
            ::.:..:.|..|...: .:.|.|..:|      :|:.:     |:|         ::.|:|| .|
Zfish   374 MSEVISVIGGISAFFI-FIFPGLCLIFVMQTEPINHRIRILLTGWG---------VVTIVIGAFI 428

  Fly   437 FGIVGCTVALMQLIRDF 453
            || ...|:|:|:|...|
Zfish   429 FG-QSTTIAVMELAHKF 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	82/401 (20%)
slc38a8b	XP_021327596.1	SLC5-6-like_sbd	32..438	CDD:320982	95/452 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750