DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment polyph and slc38a6

DIOPT Version :9

Sequence 1:	NP_610631.1	Gene:	polyph / 36161	FlyBaseID:	FBgn0033572	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_001018308.1	Gene:	slc38a6 / 336741	ZFINID:	ZDB-GENE-050522-51	Length:	449	Species:	Danio rerio

Alignment Length:	482	Identity:	99/482 - (20%)
Similarity:	194/482 - (40%)	Gaps:	100/482 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SITSFYMYNPYEKRSVEVPL------TNCDAFIS----LLKCVIGTGILAMPLAFRCSGFVMGTV 81
            ||.:...|.|..:.....||      |...:|:|    |:..::|:|||.:..|...:|.|..::
Zfish     9 SIQTVSEYEPIGEDEERTPLLPQGVQTRGSSFMSSAFNLMNAIMGSGILGLSYAMANTGTVGFSI 73

  Fly    82 MSILLMILLTYSIH--LLIADMTECCRRRRVPQVSMPEAVRIAYEEGPKWINCFGRAAGFMTTCV 144
            :.:::..|..||||  ||:.|.|         .::..||:      |.|.:|   |....:..|.
Zfish    74 LLLMVASLAAYSIHLLLLLCDKT---------GINSYEAL------GEKALN---RPGKILVACT 120

  Fly   145 LVFGQFLLCTVYLVFVS-----------KNFKEIGDHYIERYNERYYVLVACLLLLPLFMIRRLK 198
            ::.......:.||..:.           ::..|....:.|. .....:||..:::|||.::.::.
Zfish   121 ILIQNIGAMSSYLFILKTELPAAIIGFMRSDSETSGKWFEN-GVTLLILVTVIIVLPLALLPKIG 184

  Fly   199 YLVPLNLISNFLLYAGFALIMYYLFNGLP-----------NINDREMVTPPVEWIEFIAIAAFSL 252
            :|...:.|: ||....|.:::......:|           ::|..|...      :...|::.|.
Zfish   185 FLGYTSSIA-FLFMLFFTVVVVVKKWSIPCPLPINSTLSLSLNTSECTA------QLFVISSKSA 242

  Fly   253 TAVGSM-LVVEAHMA--------HPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASI 308
            .||.:| .....|.|        |..:...:....|:::....:..:...:.||..|..:|.:.:
Zfish   243 YAVPTMAFSFLCHTAVFPIYCELHRPTKRRMQRATNVSIFLSFVVYLISALFGYLTFYSHVGSEL 307

  Fly   309 TL----NIPQDEILSQFIKVFIASGIFLSYPLNGF----VVITVMFSDYENSEPRGRYRTLIEYV 365
            .|    .:|:| ||...:::.|...:.|:.||..|    .|:.:...:.|.|   ....||..:.
Zfish   308 LLAYNTYLPRD-ILVMSVRLAILLAVLLTVPLIHFPARKAVLMLCRGEREFS---WLSHTLSCFF 368

  Fly   366 VRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYNVGYGRLMWKLIRD--- 427
            :..|.|.|    ||.||::..:..:.|:.:.:.|..:.|.:.  ||       |:..:.||.
Zfish   369 ILTLVLLL----AIFVPDIKNVFGVVGSTTSTCLLFVYPGMF--FL-------RISSEPIRSFNS 420

  Fly   428 ---ILLILIGLIFGIVGCTVALMQLIR 451
               :.|::|||:.|::..:|.::..::
Zfish   421 VGAVFLLVIGLVVGVLSLSVIIVSWVQ 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	81/401 (20%)
slc38a6	NP_001018308.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25		4/15 (27%)
		SLC5-6-like_sbd	36..443	CDD:294310	92/449 (20%)
		SdaC	37..442	CDD:223884	92/447 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594512
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750