DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment polyph and slc-36.1

DIOPT Version :9

Sequence 1:	NP_610631.1	Gene:	polyph / 36161	FlyBaseID:	FBgn0033572	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_499743.2	Gene:	slc-36.1 / 259544	WormBaseID:	WBGene00012804	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	453	Identity:	118/453 - (26%)
Similarity:	216/453 - (47%)	Gaps:	16/453 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SQDQAPNRDDPDLQTEPLTIAQSITSFYMYNPYEKRSVEVPLTNCDAFISLLKCVIGTGILAMPL 69
            ::.:||.  |.::||.........||.:.    ::...|..||...|||.::|.::|||:|::||
Worm    14 NEPEAPG--DTEVQTPRRNTVSEDTSLFQ----DRLPTENSLTPEQAFIHMVKAMLGTGLLSLPL 72

  Fly    70 AFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVPQVSMPEAVRIAYEEGPKWINCFG 134
            ||:.||..:|.::::|:.::..|.:..::......|.|.....:.....:|.|.|.||.||...|
Worm    73 AFKHSGLFLGLILTVLICLICLYCMRQVVFAAHFVCNRNGRDLIDYANIMRGAVEMGPPWIKRNG 137

  Fly   135 RAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIE-RYNERYYVLVACLLLLPLFMIRRLK 198
            .....:....:...|...|.||.||::.|.::..::... ..::..::|:..:.:|.:..||||.
Worm   138 YFFKQLVNVNMFISQLGFCCVYFVFMADNLEDFFNNNTSIHLSKAVWMLLLLIPMLSICSIRRLS 202

  Fly   199 YLVPLNLISNFLLYAGFALIMYYLFNGLPNINDREMVTPPVEWIEFIAIAAFSLTAVGSMLVVEA 263
            .|.|..:.:|.:.....|:::::..:.|..|:.........:...|.....|:...|..::.:|.
Worm   203 ILAPFAMAANVVYVVAVAVVLFFFLSDLRPISSLPWFGKATDLPLFFGTVMFAFEGVAVIMPIEN 267

  Fly   264 HMAHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIAS 328
            .|..|.:::...||||.:.|.:|......|..||...|::|..:.|||:|..... |.||:...:
Worm   268 RMQSPHAFISWNGVLNSSCLVVLAIFSVTGFYGYLSLGNDVKDTATLNLPMTPFY-QTIKLMFVA 331

  Fly   329 GIFLSYPLNGFVVITVMFSDYENSEPRGRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGA 393
            .|.:||||..:|.:..:........|..: :||..|:.|...:.||.|:|..:|:||....|.||
Worm   332 CIMISYPLQFYVPMERIEKWITRKIPVDK-QTLYIYIARYSGVILTCAIAELIPHLALFISLIGA 395

  Fly   394 FSLSNLNLLCPALIDVFLNY---NVGYGRLMWKLIRDILLILIGLIFGIVGCTVALMQLIRDF 453
            ||.:::.||.|..|::..:|   .:..|  :|  |::|:|:....|....|...||:::.:.|
Worm   396 FSGASMALLFPPCIELLTSYAKNELSTG--LW--IKNIVLLTFAFIGFTTGTYSALIEIAKTF 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	96/357 (27%)
slc-36.1	NP_499743.2	SLC5-6-like_sbd	50..445	CDD:382020	106/400 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166169
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860