Protein Alignment polyph and Slc38a3

DIOPT Version :10

• Sequence 1: NP_610631.1
• Gene: polyph / 36161
• FlyBaseID: FBgn0033572
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: XP_063121016.1
• Gene: Slc38a3 / 252919
• RGDID: 628620
• Length: 527
• Species: Rattus norvegicus
• Alignment Length: 458
• Identity: 101/458 - (22%)
• Similarity: 187/458 - (40%)
• Gaps: 95/458 - (20%)

  Fly    54 SLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVPQVSMPEA 118
            :|...::|:|||.:..|...:|.::...:...:.:|.:||||||:             :.|....
  Rat    96 NLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLL-------------KSSGIVG 147

  Fly   119 VRIAYEE-GPKWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHY--IERYNERYY 180
            :| |||: |.:.....|:.|..:...:...|..   :.||..:......:...:  :|:....:|
  Rat   148 IR-AYEQLGYRAFGTPGKLAAALAITLQNIGAM---SSYLYIIKSELPLVIQTFLNLEKPTPVWY 208

  Fly   181 -------VLVACLLLLPLFMIRRLKYL-----VPLNLISNFL---LYAGFAL---IMYYLFNGLP 227
                   :||:.:::|||.::|:|.||     ..|:.:..||   :|..|.:   :.:.|.|...
  Rat   209 MDGNYLVILVSVIIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLAHNLVNATG 273

  Fly   228 NINDREMV-------TPPVEWIEFIAIAAFSL---TAVGSMLVVEAHMAHPQ---SYLGL----- 274
            |.:...:|       :.|.....|...:.|:|   ||....::..|.:.||:   .|..|
  Rat   274 NFSHMVVVEEKSQLQSEPDTAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSK 338

  Fly   275 -----FGVLNLAVLFILLSNMFF--GIIGYWRFGDNVHASIT---LNIPQDEILSQFIKVFIASG 329
                 ...|::||:::    |:|  .:.||..|.|.|.:.:.   ..:...::|...::|.:...
  Rat   339 RKMQHISNLSIAVMYV----MYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILCVRVAVLIA 399

  Fly   330 IFLSYPLNGFVV---ITVMFSDYENSEPRGRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELE 391
            :.|:.|:..|.|   |..|.  ::|.|    :..|...::....|.....:.|..||:..:..:.
  Rat   400 VTLTVPIVLFPVRRAIQQML--FQNQE----FSWLRHVLIATGLLTCINLLVIFAPNILGIFGII 458

  Fly   392 GAFSLSNLNLLCPALIDVFLNYNVGYGRLM---WKLIRDILLILIGLIFGIVG---CTVALMQLI 450
            ||.|...|..:.||:.         |.|:|   .:.:|....|| .|.|..||   .|::|..:|
  Rat   459 GATSAPCLIFIFPAIF---------YFRIMPTEKEPVRSTPKIL-ALCFAAVGFLLMTMSLSFII 513

  Fly   451 RDF 453
            .|:
  Rat   514 TDW 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:444915	87/404 (22%)
Slc38a3	XP_063121016.1	None