Protein Alignment polyph and SLC36A1

DIOPT Version :9

• Sequence 1: NP_610631.1
• Gene: polyph / 36161
• FlyBaseID: FBgn0033572
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: XP_011535882.1
• Gene: SLC36A1 / 206358
• HGNCID: 18761
• Length: 482
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 127/473 - (26%)
• Similarity: 219/473 - (46%)
• Gaps: 39/473 - (8%)

  Fly     5 SQDQAPNRDDPDLQTEPLTIAQS----ITSFYMYNPYEKRSVEVPLTNCDAFISLLKCVIGTGIL 65
            |..:..|.|..|..:..::..:|    :.:......|::.......|.....|.|||..||||:|
Human     8 STQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLL 72

  Fly    66 AMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVPQVSMPEAVRIAYEEGP-KW 129
            .:|||.:.:|.|||.:..:::.|:..:.:.:|:......|||.....|...:.|....|..| .|
Human    73 GLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSW 137

  Fly   130 INCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIERYN------------------ 176
            :.........:....|:..|...|.||.||::.|||::    ||..|
Human   138 LRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQV----IEAANGTTNNCHNNETVILTPTM 198

  Fly   177 -ERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYLFNGLPNINDREMVTPPVE 240
             .|.|:|.....|:.|..||.|:.|...:|::|..:.....:|..::...:|:.:...:|.|...
Human   199 DSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKT 263

  Fly   241 WIEFIAIAAFSLTAVGSMLVVEAHMAHPQSY-LGLF-GVLNLAVLFILLSNMFFGIIGYWRFGDN 303
            :..|...|.||...:|.:|.:|..|..|:.: |.|: |::.:.:|:|.|     |.:||.:||.|
Human   264 YPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISL-----GCLGYLQFGAN 323

  Fly   304 VHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENSEPRGRYRTLIEYVVRL 368
            :..|||||:| :..|.|.:|:..:.|||.:|.|..:|...::...:.:..|. ....:::..||.
Human   324 IQGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPE-HCELVVDLFVRT 386

  Fly   369 LFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYNVGYGRLMWKLIRDILLILI 433
            :.:.||..:||.:|.|..:..|.|:.|.|.|.|:.|.|::|...|:.|...|  .:.:|.|:.::
Human   387 VLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPL--TIFKDALISIL 449

  Fly   434 GLIFGIVGCTVALMQLIR 451
            |.:..:||...||.:||:
Human   450 GFVGFVVGTYEALYELIQ 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	106/378 (28%)
SLC36A1	XP_011535882.1	SLC5-6-like_sbd	53..459	CDD:294310	117/418 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158560
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.860