Protein Alignment polyph and SLC38A9

DIOPT Version :9

• Sequence 1: NP_610631.1
• Gene: polyph / 36161
• FlyBaseID: FBgn0033572
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001336311.1
• Gene: SLC38A9 / 153129
• HGNCID: 26907
• Length: 561
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 97/524 - (18%)
• Similarity: 172/524 - (32%)
• Gaps: 187/524 - (35%)

  Fly    32 YMYNP----YEKRSVEVPL---TNCDAFISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMIL 89
            |:|:|    |:.:|.....   |:......:...::||.||::|...:.:||..|..:.||:.:|
Human    96 YVYSPLGSAYKLQSYTEGYGKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLL 160

  Fly    90 LTYSIHLLIADMTECCRR---RRVPQVSM-------PEAVRIAYEEGPKWINCFGRAAGFMTTCV 144
            ..|           ||.|   .|....|:       |:..|       .:...||:.:..:.:.|
Human   161 TLY-----------CCYRVVKSRTMMFSLDTTSWEYPDVCR-------HYFGSFGQWSSLLFSLV 207

  Fly   145 LVFGQFLLCTVYLVFVSKNFKEIGD---HYIERYNERYYVL-------VACL------------- 186
            .:.|..:   ||.|.:|......|.   ::|...|:...:|       |.|.
Human   208 SLIGAMI---VYWVLMSNFLFNTGKFIFNFIHHINDTDTILSTNNSNPVICPSAGSGGHPDNSSM 269

  Fly   187 ----------------------------LLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYLF 223
                                        |||||...:...:....|::       |...::|.:|
Human   270 IFYANDTGAQQFEKWWDKSRTVPFYLVGLLLPLLNFKSPSFFSKFNIL-------GTVSVLYLIF 327

  Fly   224 NGLPNINDREMVTPPVEWIEFIAIAAFSLTAVG-----------SMLVVEAHMAHPQSYLGLFGV 277
                                   :..|....:|           ...|.|.....||    |.||
Human   328 -----------------------LVTFKAVRLGFHLEFHWFIPTEFFVPEIRFQFPQ----LTGV 365

  Fly   278 LNL---------------------------AVLFILLSNMFFGIIGYWRF------GDNVHASIT 309
            |.|                           |.:.:.|:.::.|::.:..|      .|.:..:..
Human   366 LTLAFFIHNCIITLLKNNKKQENNVRDLCIAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFL 430

  Fly   310 LNIPQDEILSQFIKVFIASGIFLSYPLNGFV----VITVMFSDYENSEPRGRYRTLIEYVVRLLF 370
            .|.|..:.||...::|:...:...|||.|::    ::..:|.|.        |.::  :.|.:|.
Human   431 DNFPSSDTLSFIARIFLLFQMMTVYPLLGYLARVQLLGHIFGDI--------YPSI--FHVLILN 485

  Fly   371 LFLTGA---VAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYNVGYGRLMW-KLIRDILLI 431
            |.:.||   :|...||:..:....||........:.|:||.:...:.  ..||.| |||..:.:|
Human   486 LIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQ--EERLTWPKLIFHVFII 548

  Fly   432 LIGL 435
            ::|:
Human   549 ILGV 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	81/468 (17%)
SLC38A9	NP_001336311.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		SLC5-6-like_sbd	115..556	CDD:320982	92/505 (18%)
		Important for arginine binding and amino acid transport. /evidence=ECO:0000250|UniProtKB:Q08BA4	129..134		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.830