Protein Alignment polyph and SLC38A8

DIOPT Version :9

• Sequence 1: NP_610631.1
• Gene: polyph / 36161
• FlyBaseID: FBgn0033572
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001073911.1
• Gene: SLC38A8 / 146167
• HGNCID: 32434
• Length: 435
• Species: Homo sapiens
• Alignment Length: 477
• Identity: 98/477 - (20%)
• Similarity: 186/477 - (38%)
• Gaps: 98/477 - (20%)

  Fly     6 QDQAP-NRDDPDLQTEPLTIAQSITSFYMYNPYEKRSVEVPLTNCDAFISLLKCVIGTGILAMPL 69
            :.|.| :|..|: :..|.|.|.:::|.                  .|...|:|..:|.|:|..|.
Human     2 EGQTPGSRGLPE-KPHPATAAATLSSM------------------GAVFILMKSALGAGLLNFPW 47

  Fly    70 AFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVP-QVSMPEAVRIAYEEGPKWINCF 133
            ||..:|   |.|.:.|:.::   |:..||:.:........|. |.:....||          ...
Human    48 AFSKAG---GVVPAFLVELV---SLVFLISGLVILGYAAAVSGQATYQGVVR----------GLC 96

  Fly   134 GRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIER--------YNERYYV--LVACLLL 188
            |.|.|.:.....:....::...:|..:....:::.|..:..        |.::.:.  |::.|::
Human    97 GPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVI 161

  Fly   189 LPLFMIRRL---KYLVPLNLISNFLLYAGFALIMYYLF-NGLPNINDREMVTPPVEWIEFIAIAA 249
            |||...|.:   ||...|..::...| |....:.|||: .||  :.:......|..|....::
Human   162 LPLSAPREIAFQKYTSILGTLAACYL-ALVITVQYYLWPQGL--VRESHPSLSPASWTSVFSV-- 221

  Fly   250 FSLTAVGSMLVVEAHMA----------HPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNV 304
            |.....|    .:.|.|          ...|:..|..||:|....::.|  ..|:.|:..||..|
Human   222 FPTICFG----FQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYS--LTGVYGFLTFGTEV 280

  Fly   305 HASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENS-----------EPRGRY 358
            .|.:.::.|.::::....:|..|..|...||:..|:..:||...:..|           :|.|.:
Human   281 SADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLW 345

  Fly   359 RTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGA------FSLSNLNLLCPALIDVFLNYNVGY 417
               :...:.:|::.:|.|:|:.:|:|:.:..:.|.      |....|.|:|...::. :...|..
Human   346 ---VRMPLTILWVTVTLAMALFMPDLSEIVSIIGGISSFFIFIFPGLCLICAMGVEP-IGPRVKC 406

  Fly   418 GRLMWKLIRDILLILIG-LIFG 438
            ...:|    .::.:|:| .|||
Human   407 CLEVW----GVVSVLVGTFIFG 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	83/398 (21%)
SLC38A8	NP_001073911.1	SdaC	23..431	CDD:223884	91/455 (20%)
		SLC5-6-like_sbd	23..431	CDD:294310	91/455 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158544
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750