Protein Alignment polyph and SLC36A4

DIOPT Version :9

• Sequence 1: NP_610631.1
• Gene: polyph / 36161
• FlyBaseID: FBgn0033572
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_689526.2
• Gene: SLC36A4 / 120103
• HGNCID: 19660
• Length: 504
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 108/425 - (25%)
• Similarity: 206/425 - (48%)
• Gaps: 45/425 - (10%)

  Fly    55 LLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVPQVSMPEAV 119
            |||..||||:|.:|||.:.:|.|:|.:..:.:.|:..:.:|:|:......|.|.:...:...:.|
Human    68 LLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTV 132

  Fly   120 RIAYEEGPKWINCFGRAAGFMTTCV---LVFGQFLLCTVYLVFVSKNFKEIGDHYIE-------- 173
            ..|.|..| | :|..:.|.:..:.|   ||..|...|:||:||:::|.|::.:.::|
Human   133 SFAMEVSP-W-SCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISNS 195

  Fly   174 ----------RYNERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYLFNGLPN 228
                      ..:.|.|:|.....::.|..||.||.|..|:.::|..:.....:|..|:...:|:
Human   196 TNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPD 260

  Fly   229 INDREMVTPPVEWIEFIAIAAFSLTAVGSMLVVEAHMAH----PQSYLGLFGVLNLAVLFILLSN 289
            .::..:|....::..|...|.|:...:|.:|.:|..|..    ||:       ||:.:..:....
Human   261 PHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQA-------LNIGMGIVTTLY 318

  Fly   290 MFFGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENSEP 354
            :....:||..|.|.:..|||||:|||..|.|.:|:..:.|||::|.:..:|...::.... .|:.
Human   319 VTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGI-TSKF 382

  Fly   355 RGRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFL----NYNV 415
            ..:::.:.|:.:|...:.:|.|.||.:|.|..:....||.|.|.|.|:.|.|:::..    :||:
Human   383 HTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNI 447

  Fly   416 GYGRLMWKLIRDILLILIGLIFGIVGCTVALMQLI 450
                  |.::::|.:...|::..::|..:.:.::|
Human   448 ------WMVLKNISIAFTGVVGFLLGTYITVEEII 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	100/376 (27%)
SLC36A4	NP_689526.2	SLC5-6-like_sbd	58..476	CDD:294310	107/423 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.860