DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment polyph and slc38a3b

DIOPT Version :9

Sequence 1:	NP_610631.1	Gene:	polyph / 36161	FlyBaseID:	FBgn0033572	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	XP_009300997.1	Gene:	slc38a3b / 101884924	ZFINID:	ZDB-GENE-121120-3	Length:	513	Species:	Danio rerio

Alignment Length:	512	Identity:	104/512 - (20%)
Similarity:	191/512 - (37%)	Gaps:	133/512 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DDPDLQTEPLTIAQSITSFYMYNPYEKRSVEVPLTNCD-------AFISLLKCVIGTGILAMPLA 70
            ||||     .|:|::|.  ::.|...|:.   ..|:.|       :..:|...::|:|||.:..|
Zfish    44 DDPD-----STLAENIE--FLPNSESKKP---RFTDFDGKTSFGMSVFNLGNAIMGSGILGLAYA 98

  Fly    71 FRCSGFVMGTVMSILLMILLT-------YSIHLLIADMTECCRRRRVPQVSMPEAVRIAYEEGPK 128
            ...:|.       :|.:.|||       ||||||:             :.|....:| :||:  .
Zfish    99 MANTGI-------LLFLFLLTAVAGLSCYSIHLLL-------------KSSGVVGIR-SYEQ--L 140

  Fly   129 WINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEI-----------GDHYIERYNERY-YV 181
            ....||..........:........:.||..|...|..:           |:.|:   |..| .|
Zfish   141 GFRAFGMTGKMAAAIAITLQNIGAMSSYLYIVKSEFPLVLQAFLRTDTTSGEWYL---NGNYLVV 202

  Fly   182 LVACLLLLPLFMIRRLKYL-----VPLNLISNFL---LYAGFALIMYY--------LFNGLPNIN 230
            ||:..::|||.::::|.||     ..|:.:..||   :|..|.::..:        |.:...||.
Zfish   203 LVSISIILPLALMKQLGYLGYSSGFSLSCMVFFLSAVIYKKFQILCPFEEFSANSTLTHAHSNIT 267

  Fly   231 -----------------DREMVTPPVEWIEFIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVL 278
                             ..:|.|...:....|.|.||:......:|.:...:.:| :...:..|.
Zfish   268 VDHAYHNSHVMEDDSHCHPQMFTVNSQTAYTIPILAFAFVCHPEVLPIYTELRNP-TQKKMQHVS 331

  Fly   279 NLAVLFILLSNMFF--GIIGYWRFGDNVHASITLNI----PQDEILSQFIKVFIASGIFLSYPLN 337
            |:::|  ::..|:|  .:.||..|..||...:....    |.|.:: ..:::.:.:.:.|:.|:
Zfish   332 NISIL--IMYTMYFLAALFGYLTFYTNVEPELLHTYSRIDPYDTLI-LCVRLAVLTAVTLTVPI- 392

  Fly   338 GFVVITVMFSDYENSEPRGRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLL 402
              |:..|..:..|.:.|...:..:....:.::.|.|...:.|..||:..:..:.||.|...|..:
Zfish   393 --VLFPVRRAIQEMAFPNKSFNWIRHIAIAVVLLTLINMLVIFAPNILGIFGIIGATSAPCLIFI 455

  Fly   403 CPALI----------------DVFLNYNVGYGRLMWKLIRDILLILIGLIFGIVGCT 443
            .||:.                .:|.....|.|         :|.:::.|.|.|:..|
Zfish   456 FPAVFYIRIVPKDKEPMRSTPKIFAACFAGLG---------VLFMIMSLSFIIIDWT 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	86/421 (20%)
slc38a3b	XP_009300997.1	SLC5-6-like_sbd	72..500	CDD:294310	91/469 (19%)
slc38a3b	XP_009300997.1	SdaC	72..495	CDD:223884	89/464 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594544
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940