DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpb5 and rpb-5

DIOPT Version :9

Sequence 1:	NP_001260878.1	Gene:	Rpb5 / 36160	FlyBaseID:	FBgn0033571	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_491961.1	Gene:	rpb-5 / 172412	WormBaseID:	WBGene00019246	Length:	211	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	162/208 - (77%)
Similarity:	184/208 - (88%)	Gaps:	0/208 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DDEAETYKLWRIRKTIMQLSHDRGYLVTQDELDQTLEQFKEMFGDKPSEKRPARSDLIVLVAHND 66
            |||.|||:|||||||::|:.|||||||.||||||.||.||..:||:||||:||||||.:||||||
Worm     3 DDELETYRLWRIRKTVLQMVHDRGYLVAQDELDQPLETFKVQYGDRPSEKKPARSDLTILVAHND 67

  Fly    67 DPTDQMFVFFPEEPKIGIKTIKTYCTRMQEENIHRAIVVVQGGMTPSAKQSLVDMAPKYILEQFL 131
            ||.|||||||||:.||||||||..|.:|||:||.|||:|||.|||||||||:.||||||:||.||
Worm    68 DPADQMFVFFPEDAKIGIKTIKAICQQMQEQNISRAIIVVQTGMTPSAKQSIGDMAPKYMLEHFL 132

  Fly   132 ESELLINITEHELVPEHVVMTVEEKQELLSRYKLKENMLMRIQAGDPVARYFGLKRGQVVKIIRS 196
            |:||::|||||||||||||||.|||.|||:|||||::.|.|||..|||||||||:|||||||||.
Worm   133 EAELMVNITEHELVPEHVVMTAEEKAELLARYKLKDSQLPRIQQCDPVARYFGLRRGQVVKIIRP 197

  Fly   197 SETAGRYISYRLV 209
            ||||||||:||||
Worm   198 SETAGRYITYRLV 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpb5	NP_001260878.1	PLN03111	1..210	CDD:215582	162/208 (78%)
rpb-5	NP_491961.1	PLN03111	1..211	CDD:215582	162/208 (78%)
		RNA_pol_Rpb5_N	5..93	CDD:281816	66/87 (76%)
		RNA_pol_Rpb5_C	139..210	CDD:279524	58/70 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162793
Domainoid	1	1.000	149	1.000	Domainoid score	I2720
eggNOG	1	0.900	-	-		E1_COG2012
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	334	1.000	Inparanoid score	I1416
Isobase	1	0.950	-	0	Normalized mean entropy	S297
OMA	1	1.010	-	-		QHG54766
OrthoDB	1	1.010	-	-		D1255823at2759
OrthoFinder	1	1.000	-	-		FOG0003717
OrthoInspector	1	1.000	-	-		oto19730
orthoMCL	1	0.900	-	-		OOG6_101049
Panther	1	1.100	-	-	LDO	PTHR10535
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1175
SonicParanoid	1	1.000	-	-		X3076
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750