Protein Alignment CG12942 and ZNF785

DIOPT Version :10

• Sequence 1: NP_610628.2
• Gene: CG12942 / 36158
• FlyBaseID: FBgn0033569
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_011544055.1
• Gene: ZNF785 / 146540
• HGNCID: 26496
• Length: 418
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 59/202 - (29%)
• Similarity: 89/202 - (44%)
• Gaps: 19/202 - (9%)

  Fly   384 NCPACDRIFKDQRSARKHYTRVHTPVQIAVSPTESYACTACDKVFNQKASLHSHQRFCQVKDVVH 448
            :||.|.|.|........| .|||       |....::|..|...|:|:..|..||.....:....
Human   186 SCPDCGRNFSYPSLLASH-QRVH-------SGERPFSCGQCQARFSQRRYLLQHQFIHTGEKPYP 242

  Fly   449 CSFCDQQFNSMRKYELHLQQLHAVETVHECEICRRSFKSAETLTMHRKRHS-ERHYQCGKCSLNY 512
            |..|.::|.......:| ::.|..|..:.|..|:..|.....|.:|:::|: |:.|.|..|||.:
Human   243 CPDCGRRFRQRGSLAIH-RRAHTGEKPYACSDCKSRFTYPYLLAIHQRKHTGEKPYSCPDCSLRF 306

  Fly   513 VNSAELRVHYERAHVNEEPVSCLTCGNQFQNMTLLREHEQRSHQKSKVWRCEVC--NFETKT--- 572
            ..::.|.:| .|.|..|:|..|..||.:|...:||..| :|.|..|:.:.|..|  .|:.||
Human   307 AYTSLLAIH-RRIHTGEKPYPCPDCGRRFTYSSLLLSH-RRIHSDSRPFPCVECGKGFKRKTALE 369

  Fly   573 --RWRRR 577
              ||..|
Human   370 AHRWIHR 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12942	NP_610628.2	zf-AD	21..100	CDD:462262
		C2H2 Zn finger	385..406	CDD:275368	7/20 (35%)
		C2H2 Zn finger	421..470	CDD:275368	11/48 (23%)
		C2H2 Zn finger	449..466	CDD:275371	3/16 (19%)
		C2H2 Zn finger	478..498	CDD:275368	5/19 (26%)
		C2H2 Zn finger	505..526	CDD:275368	7/20 (35%)
		C2H2 Zn finger	534..555	CDD:275368	8/20 (40%)
ZNF785	XP_011544055.1	KRAB	29..102	CDD:214630
		COG5048	<156..372	CDD:227381	56/196 (29%)
		C2H2 Zn finger	187..207	CDD:275368	7/20 (35%)
		C2H2 Zn finger	215..235	CDD:275368	7/19 (37%)
		C2H2 Zn finger	243..263	CDD:275368	4/20 (20%)
		C2H2 Zn finger	271..291	CDD:275368	5/19 (26%)
		C2H2 Zn finger	299..319	CDD:275368	7/20 (35%)
		C2H2 Zn finger	327..347	CDD:275368	8/20 (40%)
		C2H2 Zn finger	355..375	CDD:275368	7/19 (37%)