DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and PDC2

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_010366.1	Gene:	PDC2 / 851654	SGDID:	S000002488	Length:	925	Species:	Saccharomyces cerevisiae

Alignment Length:	217	Identity:	39/217 - (17%)
Similarity:	88/217 - (40%)	Gaps:	38/217 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LTLEEKMEVIQSQERN-KLSVRDLAK----RFNIGKTQAADILKH---KQSIKEGLLSGELKLNQ 69
            |:::::..:....||: |.:..:|||    .|.:.|..:...:..   ::|........|...|:
Yeast     2 LSIQQRYNICLMAERHPKWTQLELAKWAYETFQLPKIPSQGTISRLLARKSTYMNCKEHEKDANR 66

  Fly    70 MRR-NPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAK----QLAVELGHSNFSASSGWLE 129
            :|: |.|..|     ::..:|.|:.....|||:..:::..|:    ::..|....|.|.|..|:.
Yeast    67 LRKPNNLLVR-----KILQEWISQSLWNGIPITSPIIQDTAQAVWHRIPAEHREGNGSFSYKWIS 126

  Fly   130 KWRKRHNVRYNDTGDSL-------DLQEFEAILVKSEPISNKDDCDEPYPVTLIEPIYSTEEAMM 187
            .:..:.:|..:...:.|       ..:|.:.:......|..||             :::.:||.:
Yeast   127 NFLSKMDVNISVLDEELPKTPKVWTFEERDVLKAYFSKIPPKD-------------LFTLDEAFL 178

  Fly   188 QLARLKEFAKDDYASYQQLISL 209
            ......::|:.:.:|.|:.|.:
Yeast   179 SYNLPLDYAQYEASSIQRRIEV 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	10/54 (19%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	13/66 (20%)
PDC2	NP_010366.1	HTH_Tnp_Tc5	72..135	CDD:397365	13/67 (19%)
		DDE_1	198..406	CDD:367380	1/3 (33%)
		PLN02217	<716..829	CDD:215130
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840