DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and TIGD6

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001230182.1	Gene:	TIGD6 / 81789	HGNCID:	18332	Length:	521	Species:	Homo sapiens

Alignment Length:	130	Identity:	46/130 - (35%)
Similarity:	70/130 - (53%)	Gaps:	3/130 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KPRTSLTLEEKMEVIQSQERNKLSVRDLAKRFNIGKTQAADILKHKQSIKEGLLSGELKLNQMRR 72
            |.|...:|||||:|:.:.:..|.. .|:||.|.|..:..:..||.:...:|.:  .|..:...|:
Human     7 KKRRQFSLEEKMKVVGAVDSGKRK-GDVAKEFGITPSTLSTFLKDRTKFEEKV--REASVGPQRK 68

  Fly    73 NPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAKQLAVELGHSNFSASSGWLEKWRKRHNV 137
            ...|.....||:..|.||..:..:||.::|.::||||..||..||:.||.||.|||.::|.||.:
Human    69 RMRSALYDDIDKAVFAWFQEIHAKNILVTGSVIRKKALNLANMLGYDNFQASVGWLNRFRDRHGI 133

Fly 138 137
Human 134 133

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	17/51 (33%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	26/60 (43%)
TIGD6	NP_001230182.1	InsE	5..>57	CDD:225511	16/50 (32%)
		HTH	7..54	CDD:304362	16/47 (34%)
		HTH_Tnp_Tc5	75..134	CDD:281246	26/59 (44%)
		rve	207..372	CDD:304425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I10353
eggNOG	1	0.900	-	-		E1_KOG3105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1343623at2759
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	1	1.000	-	-		otm40429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850