DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and cbh1

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_594583.1	Gene:	cbh1 / 2543290	PomBaseID:	SPAC9E9.10c	Length:	514	Species:	Schizosaccharomyces pombe

Alignment Length:	184	Identity:	41/184 - (22%)
Similarity:	88/184 - (47%)	Gaps:	38/184 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RTSLTLEEKMEV--IQSQERNKLSVRDLAKRF------NIGKTQAADILKHKQS-IKEGLLS-GE 64
            |.:::|.||..:  ..:|..:::..:::.:.|      ::.::..::||..|.| :.:|.:. |:
pombe     5 RQAVSLAEKKAIRDYYNQSAHRIPQKEVTEWFRKTYNKDLSQSTISEILSPKYSYLDDGSVRLGD 69

  Fly    65 LKLNQMRRNPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAKQL------AVELGHSNFSA 123
            :|..:..:.||      :|...::|..:...|.:||||:|:::.|.:.      ...|...:|
pombe    70 IKKIRAPKFPL------LDNAVYEWLQQREVEGLPISGDMIKQAATRFWSKIPAYASLPLPDF-- 126

  Fly   124 SSGWLEKWRKRHNVRYNDTGDSLDLQEFEAILVKSEPISNKDDCDEPYPVTLIE 177
            |:|||:|:|:||.::.:....:|:..:||..              ..|||.:.|
pombe   127 SNGWLDKFRRRHYIQQSAVNQALESIKFEVF--------------REYPVHIQE 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	10/58 (17%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	19/68 (28%)
cbh1	NP_594583.1	AAT_I	<6..>103	CDD:302748	21/102 (21%)
		CENPB	76..143	CDD:197828	21/74 (28%)
		DDE_1	207..384	CDD:281213
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	41	1.000	Domainoid score	I3700
eggNOG	1	0.900	-	-		E1_KOG3105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840