DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and cbp1

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_596460.1	Gene:	cbp1 / 2539971	PomBaseID:	SPBC1105.04c	Length:	522	Species:	Schizosaccharomyces pombe

Alignment Length:	206	Identity:	48/206 - (23%)
Similarity:	94/206 - (45%)	Gaps:	49/206 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GRVRKPRTSLTLEEKMEVIQ--SQERNKLSVRDLAKRF------NIGKTQAADILKHKQSIKEGL 60
            |:::  |.::|..||..:..  .|.:|:...:||.:.|      :|.:...:.||..|.|..:..
pombe     2 GKIK--RRAITEHEKRALRHYFFQLQNRSGQQDLIEWFREKFGKDISQPSVSQILSSKYSYLDNT 64

  Fly    61 LS--GELKLNQMRRNPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAKQLAVELGHS---- 119
            :.  .::|.|:..:.||      ::...|:|..: :.::..:|||.:    |:.|..|.|.
pombe    65 VEKPWDVKRNRPPKYPL------LEAALFEWQVQ-QGDDATLSGETI----KRAAAILWHKIPEY 118

  Fly   120 ------NFSASSGWLEKWRKRHNVRYNDTGDSLDLQEFEAILVK-----SEPISNKDDCDEPYPV 173
                  ||  |:||||.:||||.:.      :::.|..|::::.     ::|:|...|...   :
pombe   119 QDQPVPNF--SNGWLEGFRKRHILH------AINEQPTESVVLNNTEPPNDPLSRVYDVTR---L 172

  Fly   174 TLIEPIYSTEE 184
            |.|..|::.:|
pombe   173 TNINDIFTMQE 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	14/60 (23%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	20/72 (28%)
cbp1	NP_596460.1	CENPB	76..144	CDD:197828	22/86 (26%)
cbp1	NP_596460.1	DDE_1	208..385	CDD:281213
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	41	1.000	Domainoid score	I3700
eggNOG	1	0.900	-	-		E1_KOG3105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930