DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and cbh2

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_596738.1	Gene:	cbh2 / 2539728	PomBaseID:	SPBC14F5.12c	Length:	514	Species:	Schizosaccharomyces pombe

Alignment Length:	205	Identity:	49/205 - (23%)
Similarity:	95/205 - (46%)	Gaps:	44/205 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSGRVRKPRTSLTLEEKMEVIQS--QERNKLSVRDLAKRF------NIGKTQAADILKHKQSIK 57
            ||..|    |.:|||.||..:.:.  :...|.|.::|...|      .:.::..:.||..|....
pombe     1 MPPLR----RQALTLAEKKAIRKHYFESATKPSQQELISWFEEHFHKKLAQSTVSSILSSKNEFL 61

  Fly    58 EGLLSGELKLNQMRRNPLSQRGAQ--IDEMCFDWFSRVRTENIPISGEMVRKKAKQL------AV 114
            :.|   :.:.:|:|||   ::|..  ::....||.:|::.::..|:|..::|.|.:|      ..
pombe    62 DNL---DAENSQIRRN---RQGKYPILENALIDWQTRLQKQDGAITGNAIKKSAAELWRRIPEYS 120

  Fly   115 ELGHSNFSASSGWLEKWRKR---HNVRYNDTGDSLDLQEFEAILVKSEPISNKDDCDEPYPVTLI 176
            ||....|  |:|||||::||   |.::......|::...:|..:|:.:.:           ::|.
pombe   121 ELPIPEF--SNGWLEKFKKRCLKHGLKLQGESTSVNQGTYEENMVQIQEL-----------ISLF 172

  Fly   177 EP--IYSTEE 184
            :|  |::.:|
pombe   173 DPKDIFNMDE 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	13/60 (22%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	21/73 (29%)
cbh2	NP_596738.1	CENPB	76..139	CDD:197828	19/64 (30%)
cbh2	NP_596738.1	DDE_1	207..384	CDD:281213
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	41	1.000	Domainoid score	I3700
eggNOG	1	0.900	-	-		E1_KOG3105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930