DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and Tigd5

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_848761.2	Gene:	Tigd5 / 105734	MGIID:	2145902	Length:	642	Species:	Mus musculus

Alignment Length:	135	Identity:	33/135 - (24%)
Similarity:	65/135 - (48%)	Gaps:	13/135 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RTSLTLEEKMEVIQ---SQERNKLSVRDLAKRFNIGKTQAADILKHKQSIKEGL--LSGELKLNQ 69
            |.:.::::|::.|:   ..||.....||    |.:........||.:..::..|  |.||:...:
Mouse    63 RKAYSIKDKLQAIERVKGGERQASVCRD----FGVPGGTLRGWLKDEPKLRWFLDQLGGEVGTQR 123

  Fly    70 MRRNPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAKQLAVEL--GHSNFSASSGWLEKWR 132
            .:....::.  :||...:.||..:|...:|:||.:::.:|:..|.::  ....|.||.||..:|:
Mouse   124 KKMRLANEE--EIDRAVYSWFLTLRQHGVPLSGPVIQAQAEAFARQIYGPECTFKASHGWFWRWQ 186

  Fly   133 KRHNV 137
            |||.:
Mouse   187 KRHGI 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	10/52 (19%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	19/62 (31%)
Tigd5	NP_848761.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..54
		HTH	63..112	CDD:304362	10/52 (19%)
		HTH_Tnp_Tc5	132..192	CDD:281246	19/62 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..238
		rve	280..486	CDD:304425
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	375..400
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	548..581
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1343623at2759
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	1	1.000	-	-		otm42505
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920