DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and Tigd2

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001292109.1	Gene:	Tigd2 / 100912924	RGDID:	1559612	Length:	526	Species:	Rattus norvegicus

Alignment Length:	197	Identity:	53/197 - (26%)
Similarity:	95/197 - (48%)	Gaps:	41/197 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RKPRTSLTLEEKMEVIQSQERNKLSVRDLAKRFNIGKTQAADILKHKQSI-----KEGLLSGELK 66
            ::.|..||:::|:::|:..|... |.:.|:..:.||::...||.|:|:.|     .....||..|
  Rat     4 KRKRVVLTIKDKLDIIKKLEEGN-SFKKLSVLYGIGESTVRDIKKNKERIINYANNSDPTSGVSK 67

  Fly    67 LNQMRRNPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAKQLAVELG-HSNFSASSGWLEK 130
            ...|:    |....::|.:..:||::.:|..||:||.:..|:|:.....|| ..:|:||||||.:
  Rat    68 RKSMK----SSTYEELDRVMIEWFNQQKTNGIPVSGTICAKQARFFFDALGMEGDFNASSGWLTR 128

  Fly   131 WRKRHNV----------RYNDTGDSL---DLQEFEAILVKSEPISNKDDCDEPYPVTLIEPIYST 182
            :::||.:          :.::|..|.   :.|||    ||.|.:             |.|.||..
  Rat   129 FKQRHGIPKAAGKGTKLKGDETAASEFCGNFQEF----VKRENL-------------LPEQIYGA 176

  Fly   183 EE 184
            ::
  Rat   177 DQ 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	15/57 (26%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	21/73 (29%)
Tigd2	NP_001292109.1	HTH	4..52	CDD:389747	14/48 (29%)
		HTH_Tnp_Tc5	76..135	CDD:367403	21/58 (36%)
		DDE_1	207..385	CDD:367380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1343623at2759
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	1	1.000	-	-		otm44569
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920