DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30020 and znf513a

DIOPT Version :9

Sequence 1:	NP_610627.2	Gene:	CG30020 / 36156	FlyBaseID:	FBgn0050020	Length:	1309	Species:	Drosophila melanogaster
Sequence 2:	NP_001296396.1	Gene:	znf513a / 568216	ZFINID:	ZDB-GENE-030131-9895	Length:	548	Species:	Danio rerio

Alignment Length:	658	Identity:	133/658 - (20%)
Similarity:	215/658 - (32%)	Gaps:	224/658 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   646 PV-VDGDDIVIDNNNISLDFDAENLFE---DFEEEEDD--TVADEEDEAD--------NEDENDN 696
            || :|.:|.|......:|.|:::.|..   :|.:.::|  .:..|:..||        .::||
Zfish    11 PVKLDSEDGVGTVRPTNLTFESDFLLGQELEFSDPDNDQKIIGLEKFSADISLPGFPLGDEEN-- 73

  Fly   697 NDAATDQNLLLTSDDDDVDDFDDEQSKHLQK----------------------------PYCIYC 733
               :....|.:.||.||:...:.|:.:.:.:                            |||:.|
Zfish    74 ---SPFSRLSMESDADDLRATESEREERVSESAFPSYLSCRGCGQLLEDPLGPGMDLVGPYCMRC 135

  Fly   734 NKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIKHYKTVHKRMPTRDMVQAK---GDKV 795
            .|.....       .|.|       :||:.|                      .:||:   |...
Zfish   136 CKGNVEG-------IVDR-------KLCSGL----------------------GLQAESRGGGNE 164

  Fly   796 SVARTNIEKLYPGRIKNPMLMCAKCPFECESDSEMRKHLNAHHGINDGVSEHANEVFIIRKLPFE 860
            ........||:         .|..|.|.....:.:::|:..|:|                :.|:.
Zfish   165 GTGEDGSLKLH---------SCTLCGFTSRYTNHVKRHMKTHNG----------------EKPYG 204

  Fly   861 CPRCIRSFAAKTTLSRHLQRSHLVDTIIEMQTPHCGE----AITTTMATSSSTISEPVNSVTVDG 921
            ||.|..:.|....|.|||:             .|.||    ..|.|.|.||      :.::.
Zfish   205 CPLCSYASAQLVNLQRHLR-------------IHTGEKPYKCNTCTFACSS------LGNLK--- 247

  Fly   922 QHNEMMQTDVGAEKMTEAL-GNGDGNEEGGTDDGTGVKAEPAVPEEELDPVTLDAATAVTTTAIA 985
            :|..|..|....:.:|:.: |||..:.....      |.:.|||               ..|.:|
Zfish   248 RHQRMHATIGPGQSVTQPVSGNGLNHSTAAQ------KEKEAVP---------------APTEVA 291

  Fly   986 AAISAAA----AATATSLESPVATTASSSTTLFPTPTPFDFDYDIMRDEAQQSSPNIHDVSKALS 1046
            .|:.:..    ......|::                      :|.:| .|||:|..:....:|.|
Zfish   292 GAVRSVTRPHMGRDGNYLQT----------------------FDGLR-LAQQTSTGVLQSGQAAS 333

  Fly  1047 DNAS-------SSCPINESYKLLSTTALETSPAKGLRSNSRLHRSSIHICKLCNQTFDELGKLVK 1104
            ..|:       .:|       .|...||:....           ||..||..|  |.:.|.|
Zfish   334 QPAALPPMFFPFTC-------RLCGMALDDEDG-----------SSAQICAKC--TLEMLTK--- 375

  Fly  1105 HEMELHSNTERSRWGYQHKCAICNTSYRTLTLLKFHMKRHSNRKS-QCKLCPKSFVTIAELERHT 1168
               :.| .....|....:.||.|.........|..|||.||..|. :|..|..:......|:||.
Zfish   376 ---DTH-GCPAERGDKVYTCAACPFLTHYPNHLARHMKTHSGEKPYKCPQCDYASAHFDNLKRHH 436

  Fly  1169 KAKHSKDKTLRCFMDGCRKTFAFKHHLIRHQKASHLSTRYICPVCNKEEKSNVHLKNHMSVHKGE 1233
            :. |:.:|..:|.:  |........:|.|||:....:..:.|.:||.....:::||.||..|.||
Zfish   437 RV-HTGEKPYKCHL--CDYACGNLANLKRHQRVHSGAKPFQCAICNYSCNQSMNLKRHMLRHTGE 498

  Fly  1234 ITYKCPKC 1241
            ..:||.:|
Zfish   499 KPHKCQEC 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30020	NP_610627.2	zf-AD	25..106	CDD:285071
		C2H2 Zn finger	369..389	CDD:275368
		C2H2 Zn finger	397..418	CDD:275368
		C2H2 Zn finger	442..460	CDD:275368
		C2H2 Zn finger	730..750	CDD:275368	3/19 (16%)
		C2H2 Zn finger	758..777	CDD:275368	3/18 (17%)
		C2H2 Zn finger	1089..1110	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1124..1144	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1151..1172	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1180..1203	CDD:275368	6/22 (27%)
		C2H2 Zn finger	1210..1230	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1238..1254	CDD:275368	2/4 (50%)
znf513a	NP_001296396.1	C2H2 Zn finger	177..197	CDD:275368	4/19 (21%)
		zf-H2C2_2	189..214	CDD:290200	7/40 (18%)
		COG5048	201..>503	CDD:227381	88/397 (22%)
		C2H2 Zn finger	205..225	CDD:275368	8/32 (25%)
		zf-H2C2_2	217..242	CDD:290200	10/37 (27%)
		C2H2 Zn finger	233..253	CDD:275368	6/28 (21%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
		zf-H2C2_2	403..428	CDD:290200	9/24 (38%)
		C2H2 Zn finger	419..439	CDD:275368	5/20 (25%)
		zf-H2C2_2	431..454	CDD:290200	7/25 (28%)
		C2H2 Zn finger	447..467	CDD:275368	6/21 (29%)
		zf-H2C2_2	459..484	CDD:290200	7/24 (29%)
		C2H2 Zn finger	475..495	CDD:275368	7/19 (37%)
		zf-H2C2_2	487..510	CDD:290200	10/20 (50%)
		C2H2 Zn finger	503..523	CDD:275368	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100