Protein Alignment CG30020 and znf423

DIOPT Version :10

• Sequence 1: NP_610627.2
• Gene: CG30020 / 36156
• FlyBaseID: FBgn0050020
• Length: 1309
• Species: Drosophila melanogaster
• Sequence 2: XP_073785446.1
• Gene: znf423 / 566696
• ZFINID: ZDB-GENE-030131-4368
• Length: 1376
• Species: Danio rerio
• Alignment Length: 1476
• Identity: 256/1476 - (17%)
• Similarity: 421/1476 - (28%)
• Gaps: 582/1476 - (39%)

  Fly    79 CLECSKSLQVAYYFLQNALRAHE-----------ILCRKLCPKVSKRLNGTLAQEQEKPACAEPV 132
            |..|.||.....|     |:.||           ..|.:|......|.........:|
Zfish   156 CQFCDKSFSRLSY-----LKRHEQIHSDKLPFKCTFCSRLFKHKRSRDRHVKLHTGDK------- 208

  Fly   133 QPLKTMRHECQVCGVVLYNRLELKQHIRQHAEGLSYNCKLC----SFTSLKQRTLFEHY------ 187
                  ::.||.|.........||.|::.|:....:.|.:|    |.||..|..:..|.
Zfish   209 ------KYSCQECEAAFSRSDHLKIHLKTHSSSKPFKCSICKRGFSSTSSLQSHMQAHRKNKEHL 267

  Fly   188 --------------VTMHNMPL-------------SQAEEYVKSKHLPAPKEEEVKAV-CTLEDM 224
                          ||..:..|             .:.|::|.::|.......|::.: |
Zfish   268 AKKDQGKRDGSSSDVTEQDQDLYMCDYCEETFSQTDELEKHVLTQHPQLSDRAELQCIHC----- 327

  Fly   225 ELLIPTVLRPEDYVQPH-------------------P-------HIDNDQLRDIDHQLAVSMDEP 263
                |.:...|..:..|                   |       |:|:.:..|..:..| |.|..
Zfish   328 ----PEIFSDEGTLLTHIDRTHANKKHKCPMCAEQFPSVEDVYCHLDSHRQPDSSNHSA-SPDPV 387

  Fly   264 VPSVDSLTSTLPPMDTPNVSIGTEYLVLPDGSLQQVNGSGVVIEYIDDSKPNSSSNVNVSLQNLL 328
            :.||.|::|.     ||:.|...|....||.:|:.......:....|......|..|..|.....
Zfish   388 LGSVASMSSA-----TPDSSASLERGSTPDSTLKPGQSRRKLAPSSDHDDGTWSGKVTYSCPYCS 447

  Fly   329 SSHNDPMDIDVNELIVEEMMPQIRIKPKPAVIGTSIHKHKCKFCPKTFSTVARLKSH-------- 385
            ..       |.|.|.|.|:..:.....||.      ..|.|:.|.:|..|:..|..|
Zfish   448 KR-------DFNSLAVLEIHLKTIHADKPQ------QSHTCQLCLETLPTLYNLNEHVRKAHRSS 499

  Fly   386 --------QLTHSNLPKFFCDQC-DFYSLRSADL--IQHYKMVHHRVDENGKTGKEQAQGIESRV 439
                    .|..||:..|.|:.| |.:    ||:  :|.:..|.|.:......|....:|  :..
Zfish   500 GNSASNFPLLQFSNVSAFHCNYCPDMF----ADINSLQEHIRVSHCLSGGVVAGSTTLEG--NHA 558

  Fly   440 YSCDMCLFETSTVSQLRTHYKERHTVQPTEVQLRPSWTGEPTTTRGVAAKQQTPAKILNHTDIPL 504
            :.|:.|.....|.|.|..|.::.|                 .::.|...|.::|
Zfish   559 FFCNQCSMGFLTESSLTEHIQQTH-----------------CSSVGGVTKMESP----------- 595

  Fly   505 GIKYPPGVLETQAPLPQPVVHQPMPDPMQ-QTEPMATTSTTITESGDINVVVDATPLFYAATSNS 568
                               |.||....|: .:.|..|.|                |:|     .|
Zfish   596 -------------------VLQPSQSFMEVYSCPYCTNS----------------PIF-----GS 620

  Fly   569 LLVTNPAPVTTVEETTGTASNHAFGIFPEISEGNLPVNEAVQQAPANSSSVSVFGDMQDFIDNTD 633
            ||          :.|.....||.          |:|:        ||:.......|:.....:.:
Zfish   621 LL----------KLTKHIKENHK----------NIPL--------ANNKRKVKVADLSPASSDVE 657

  Fly   634 VAA--ICTIPADGMPVVDGDDIVIDNNNISLDFDAENLFEDFEEEEDDTVADEEDEADNEDENDN 696
            :::  ...:..|..|.|...|...  |...|.|.:   ||.|:..
Zfish   658 ISSPKRHRVTGDSTPAVANGDYPC--NQCDLRFSS---FEGFQAH-------------------- 697

  Fly   697 NDAATDQNLLL---TSDDDDVDDFDDEQS--KHLQKPY--------CIYCNKKFTSQYKFENHMF 748
              ..:...|||   :....:.:|||.:::  :||...|        |..|:|:|:|....:.|:.
Zfish   698 --LKSHLELLLRRQSCPQCNKEDFDSQEALLQHLTIHYTTTSTQYVCESCDKQFSSVDDLQKHLL 760

  Fly   749 VHRGLAPYRCELCTNLYNMKRLLIKHYKTVHKRMPTRDMVQAKGDKVSVARTNIEKLYPGRIKNP 813
            .......|.|.||..:::.|..:..|                    ::|..:|.:|:|
Zfish   761 DMHTFVLYHCTLCQEVFDSKVSIQVH--------------------LAVKHSNEKKMY------- 798

  Fly   814 MLMCAKCPFECESDSEMR---KHLNAHHGINDGVSEHA------NEVF----------IIRKLPF 859
              .|..|.::...:|:::   ||.:..|..:.|....|      .|.|          ......:
Zfish   799 --RCTACAWDFRKESDLQLHVKHSHLGHPASTGAPGKARKCIFCGETFGTEVELQCHITTHSKKY 861

  Fly   860 ECPRCIRSFAAKTTLSRHLQRSHLVDTIIEMQTPHCGEAITTTMATSSSTISEPVNSVTVDGQHN 924
            .|..|.::|.|...|.|||:..|.:                                  .||
Zfish   862 NCRLCGKAFHAIVLLERHLREKHCI----------------------------------FDG--- 889

  Fly   925 EMMQTDVGAEKMTEALGNGDGNEEGGTDDGTGVKAEPAVPEEELDPVTLDAATAVTTTAIAAAIS 989
                            |||:||  ||:.:||                    ...||.::..:...
Zfish   890 ----------------GNGNGN--GGSQNGT--------------------PNGVTQSSKRSTAG 916

  Fly   990 AAAAATATSLESPVATTASSSTTLFPTPTPFDFDYD---------------IMRDEAQQSSPNIH 1039
            :.|||....|::.:....|..|......:..:.:.|               .|....|......|
Zfish   917 STAAAEQADLQNMLLKGGSQETANSHEASGGEEELDASEPMYACDICGAAYTMESLLQNHRLRDH 981

  Fly  1040 DVSKALSDNASSSCPI-----NESYKLLSTTALETSPAKGLRSNSRLHR--SSIHICKLCNQTFD 1097
            ::.....|..|.....     |....:.|.|....:   |||.:::.||  :..::|.:|.:.|.
Zfish   982 NIRPGEDDAGSRKKKADFIKGNHKCNVCSRTFFSEN---GLREHAQTHRGPAKHYMCPICGERFP 1043

  Fly  1098 ELGKLVKHEM----------------------------ELHSNTERSRWGYQHKCAICNTSYRTL 1134
            .|..|.:|::                            ::|.:...|..|:  :|.:|..:..:.
Zfish  1044 SLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF--RCVVCMQTVTST 1106

  Fly  1135 TLLKFH----------------------------------------------------------- 1140
            ..||.|
Zfish  1107 LELKIHGTFHMQKLSSSGGSGGGGGSASSSPNGQLQAHKLYKCALCLKDFKNKQELVKIDVNGLP 1171

  Fly  1141 -------MKRHSNRKS------------------QCKLCPKSFVTIAELERHTKAKHS------- 1173
                   |.|.:|.:|                  :|..|...|.|:.:||.|.:..|:
Zfish  1172 YGLCAGCMSRGTNGQSPTVVVTPQEAGDKGTTGLRCSECAVKFETLEDLESHIQVDHTEMSPETS 1236

  Fly  1174 ------------KDKTLRCFMDGCRKTFAFKHHLIRHQKASHL----------STRYICPVCNKE 1216
                        |.||.:|..  |:.||..:..:..| .|:|:          ...:.|.:||:.
Zfish  1237 GAKKVTDASPVPKKKTYQCIK--CQMTFETEREIQIH-VANHMIGEPAQLQEEGINHECKLCNQM 1298

  Fly  1217 EKSNVHLKNHMSVHKGE---ITYKCPKCDRSYLRRGRLVTHALIIH 1259
            ..|...|..|:..|..|   .|:|||.|...:::..:|..|...:|
Zfish  1299 FDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVH 1344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30020	NP_610627.2	zf-AD	25..103	CDD:214871	8/34 (24%)
		C2H2 Zn finger	369..389	CDD:275368	7/35 (20%)
		C2H2 Zn finger	397..418	CDD:275368	6/23 (26%)
		C2H2 Zn finger	442..460	CDD:275368	6/17 (35%)
		C2H2 Zn finger	730..750	CDD:275368	6/19 (32%)
		C2H2 Zn finger	758..777	CDD:275368	5/18 (28%)
		C2H2 Zn finger	1089..1110	CDD:275368	6/48 (13%)
		C2H2 Zn finger	1124..1144	CDD:275368	6/85 (7%)
		C2H2 Zn finger	1151..1172	CDD:275368	7/20 (35%)
		C2H2 Zn finger	1180..1203	CDD:275368	6/22 (27%)
		C2H2 Zn finger	1210..1230	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1238..1254	CDD:275368	4/15 (27%)
znf423	XP_073785446.1	None